Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SCN1A | P35498 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20503355 | 1.00 | LMNA (0.51) | LMNATSHRF2TDP1SLC6A3 | |
| SCHEMBL8836430 | 0.91 | TSHR (0.42) | LMNATSHRTDP1CYP2D6KMT2A | |
| SCHEMBL7934397 | 0.90 | LMNA (0.49) | LMNATSHRF2TDP1CYP2D6 | |
| SCHEMBL7934395 | 0.90 | LMNA (0.49) | LMNATSHRF2TDP1CYP2D6 | |
| SCHEMBL6551288 | 0.89 | LMNA (0.47) | LMNATSHRTDP1KMT2AMAPK1 | |
| SCHEMBL27866085 | 0.88 | SMN1; SMN2 (0.39) | LMNATSHRKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL22439055 | 0.87 | SOAT2 (0.49) | LMNATSHRTDP1KMT2ACES2 | |
| SCHEMBL21528269 | 0.87 | SOAT2 (0.49) | LMNATSHRTDP1KMT2ACES2 | |
| SCHEMBL6552638 | 0.87 | SOAT2 (0.49) | LMNATSHRTDP1KMT2ACES2 | |
| SCHEMBL6552841 | 0.87 | SOAT2 (0.49) | LMNATSHRTDP1KMT2ACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230051453-A1 | BIOSYNTHETIC PLATFORM FOR THE PRODUCTION OF OLIVETOLIC ACID AND ANALOGUES OF OLIVETOLIC ACID | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-02-16 | — | — | US | disclosed |
| EP-3377473-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX Pharmaceuticals, Inc. (US) | 2018-09-26 | — | — | EP | disclosed |