Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.47 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20503291 | 0.94 | SKP2 (0.53) | PPARAPPARGSKP2 | |
| SCHEMBL7246712 | 0.87 | TRPV1 (0.56) | PPARAPPARGKAT8RARB | |
| SCHEMBL7252668 | 0.87 | TRPV1 (0.56) | PPARAPPARGKAT8RARB | |
| SCHEMBL1022843 | 0.86 | PPARA (0.50) | PPARAPPARGKAT8 | |
| SCHEMBL28884750 | 0.85 | CYP4A11 (0.43) | PPARASKP2 | |
| SCHEMBL9854497 | 0.80 | RARB (0.57) | RARB | |
| SCHEMBL4621536 | 0.79 | AKT1 (0.44) | PPARAPPARGSKP2 | |
| SCHEMBL14280099 | 0.77 | SKP2 (0.49) | PPARAPPARGSKP2 | |
| SCHEMBL1837008 | 0.77 | THRB (0.66) | RARB | |
| SCHEMBL1838051 | 0.77 | THRB (0.66) | RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108884058-B | Macrocyclic broad spectrum antibiotics | 阿奇克斯制药公司 | 2022-04-29 | — | — | CN | disclosed |
| EP-3377473-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX Pharmaceuticals, Inc. (US) | 2018-09-26 | — | — | EP | disclosed |