Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | IKBKB | O14920 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 2/20 | 0.42 |
| ▸ | CASP7 | P55210 | 2/20 | 0.42 |
| ▸ | BTK | Q06187 | 6/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2044387 | 1.00 | HSD17B10 (0.46) | HSD17B10ALDH1A1MAPTALOX15MAPK1 | |
| SCHEMBL2044381 | 0.93 | HSD17B10 (0.47) | HSD17B10ALDH1A1MAPTALOX15MAPK1 | |
| SCHEMBL4094487 | 0.68 | SMN1; SMN2 (0.41) | HSD17B10ALDH1A1MAPTALOX15MAPK1 | |
| SCHEMBL2021582 | 0.65 | SMN1; SMN2 (0.45) | HSD17B10ALDH1A1MAPTALOX15MAPK1 | |
| SCHEMBL4094478 | 0.65 | MAPT (0.42) | HSD17B10ALDH1A1MAPTALOX15MAPK1 | |
| SCHEMBL30159841 | 0.63 | MAPT (0.69) | HSD17B10ALDH1A1MAPTALOX15MAPK1 | |
| SCHEMBL2021575 | 0.63 | MAPT (0.43) | HSD17B10ALDH1A1MAPTALOX15MAPK1 | |
| SCHEMBL30159934 | 0.61 | MAPT (0.67) | HSD17B10ALDH1A1MAPTALOX15MAPK1 | |
| SCHEMBL19715437 | 0.61 | BTK (0.64) | HSD17B10ALDH1A1MAPTALOX15MAPK1 | |
| SCHEMBL150478 | 0.61 | ALOX15 (1.00) | HSD17B10ALDH1A1MAPTALOX15MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110160180-A1 | Cannabinoid Receptor Ligands | ASTRAZENECA AB (SE) | 2011-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110160180-A1 | Cannabinoid Receptor Ligands | CNR1, CNR2, OPRL1 | HSD17B10 3976/4885ALDH1A1 2240/4885MAPT 3104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.