Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 7/20 | 0.72 |
| ▸ | MGLL | Q99685 | 8/20 | 0.59 |
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.55 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20503500 | 0.99 | FAAH (0.72) | FAAHMGLLABHD6PLA2G7CYP2D6 | |
| SCHEMBL20503476 | 0.93 | FAAH (0.63) | FAAHMGLLABHD6PLA2G7CYP2D6 | |
| SCHEMBL20503654 | 0.92 | FAAH (0.62) | FAAHMGLLABHD6PLA2G7CYP2D6 | |
| SCHEMBL20503623 | 0.92 | FAAH (0.73) | FAAHMGLLABHD6PLA2G7CYP2D6 | |
| SCHEMBL20503486 | 0.92 | FAAH (0.66) | FAAHMGLLABHD6PLA2G7CYP2D6 | |
| SCHEMBL21271370 | 0.91 | FAAH (0.61) | FAAHMGLLABHD6PLA2G7CYP2D6 | |
| SCHEMBL21271355 | 0.91 | FAAH (0.63) | FAAHMGLLABHD6PLA2G7CYP2D6 | |
| SCHEMBL20503599 | 0.91 | FAAH (0.61) | FAAHMGLLABHD6PLA2G7CYP2D6 | |
| SCHEMBL21271359 | 0.91 | FAAH (0.70) | FAAHMGLLABHD6PLA2G7CYP2D6 | |
| SCHEMBL31168756 | 0.91 | FAAH (0.70) | FAAHMGLLABHD6PLA2G7CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108601769-B | Pyrazole compounds and methods of making and using the same | H.隆德贝克有限公司 | 2021-09-03 | — | — | CN | disclosed |
| EP-3377060-B1 | PYRAZOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND USES THEREOF | LUNDBECK LA JOLLA RESEARCH CENTER INC (US) | 2020-08-19 | — | — | EP | disclosed |
| EP-3377060-B1 | PYRAZOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND USES THEREOF | LUNDBECK LA JOLLA RESEARCH CENTER INC (US) | 2020-08-19 | — | — | EP | disclosed |
| US-20190256494-A1 | PYRAZOLE COMPOUNDS AND METHODS OF MAKING AND USING SAME | H. LUNDBECK A/S (DK) | 2019-08-22 | — | — | US | disclosed |
| US-20190256494-A1 | PYRAZOLE COMPOUNDS AND METHODS OF MAKING AND USING SAME | H. LUNDBECK A/S (DK) | 2019-08-22 | — | — | US | disclosed |
| EP-3377060-A1 | PYRAZOLE COMPOUNDS AND METHODS OF MAKING AND USING SAME | Abide Therapeutics, Inc. (US) | 2018-09-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190256494-A1 | PYRAZOLE COMPOUNDS AND METHODS OF MAKING AND USING SAME | ABHD6, ABHD16A, RABL6 | FAAH 16/4885MGLL 21/4885ABHD6 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.