Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.42 |
| ▸ | MGLL | Q99685 | 12/20 | 0.42 |
| ▸ | ABHD6 | Q9BV23 | 6/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20503582 | 0.86 | MGLL (0.46) | MGLLABHD6CYP2D6PLA2G7 | |
| Trifluoroacetic Acid SCHEMBL28618771 | 0.85 | CHRM3 (0.38) | FAAHMGLLABHD6NOTUM | |
| SCHEMBL20567654 | 0.85 | FAAH (0.65) | FAAHMGLL | |
| SCHEMBL30419290 | 0.85 | FAAH (0.65) | FAAHMGLL | |
| SCHEMBL20503642 | 0.83 | NOTUM (0.42) | CYP2D6SIGMAR1NOTUM | |
| SCHEMBL22350686 | 0.79 | FAAH (0.48) | FAAHMGLL | |
| SCHEMBL20571263 | 0.79 | NOTUM (0.43) | FAAHMGLLSIGMAR1NOTUM | |
| SCHEMBL20503532 | 0.79 | FAAH (0.46) | FAAHMGLL | |
| SCHEMBL20571297 | 0.78 | MGLL (0.45) | FAAHMGLLABHD6CYP2D6PTGDR2 | |
| SCHEMBL20503399 | 0.76 | MGLL (0.50) | FAAHMGLLABHD6CYP2D6PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3377060-A1 | PYRAZOLE COMPOUNDS AND METHODS OF MAKING AND USING SAME | Abide Therapeutics, Inc. (US) | 2018-09-26 | — | — | EP | disclosed |