Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 7/20 | 0.69 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.69 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.69 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.69 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.69 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.69 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.69 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.69 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.69 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.69 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.69 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.66 |
| ▸ | KDM1A | O60341 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28553512 | 0.90 | MAPT (0.77) | HDAC1HDAC8HDAC6HDAC5HDAC4 | |
| SCHEMBL8012743 | 0.89 | TRPV1 (0.81) | HDAC1HDAC8HDAC6HDAC5HDAC4 | |
| SCHEMBL17064258 | 0.86 | HDAC3 (0.59) | HDAC1HDAC8HDAC6HDAC5HDAC4 | |
| SCHEMBL20508340 | 0.86 | TRPV1 (0.73) | HDAC1HDAC8HDAC6HDAC5HDAC4 | |
| SCHEMBL6961827 | 0.84 | KDM1A (0.68) | HDAC1HDAC8HDAC6HDAC5HDAC4 | |
| SCHEMBL17986848 | 0.84 | PLAAT3 (0.51) | HDAC1HDAC8HDAC6HDAC5HDAC4 | |
| SCHEMBL6517887 | 0.84 | MAPT (0.77) | HDAC1HDAC8HDAC6HDAC5HDAC4 | |
| SCHEMBL13581272 | 0.84 | NPC1 (0.71) | HDAC1HDAC8HDAC6HDAC5HDAC4 | |
| SCHEMBL18422082 | 0.83 | TRPV1 (0.73) | HDAC1HDAC8HDAC6HDAC5HDAC4 | |
| Hydrochloric Acid SCHEMBL8392010 | 0.83 | KDM1A (0.66) | HDAC1HDAC8HDAC6HDAC5HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119192065-A | Anticancer compounds | 悉尼大学 | 2024-12-27 | — | — | CN | disclosed |
| EP-3250551-B1 | ANTI-CANCER COMPOUNDS | UNIV SYDNEY (AU) | 2022-11-09 | — | — | EP | disclosed |
| US-10745355-B2 | Anti-cancer compounds | THE UNIVERSITY OF SYDNEY (AU) | 2020-08-18 | — | — | US | disclosed |
| US-10745355-B2 | Anti-cancer compounds | THE UNIVERSITY OF SYDNEY (AU) | 2020-08-18 | — | — | US | disclosed |
| US-20180273478-A1 | ANTI-CANCER COMPOUNDS | THE UNIVERSITY OF SYDNEY (AU) | 2018-09-27 | — | — | US | disclosed |
| CN-107207437-A | Anticancer compounds | 悉尼大学 | 2017-09-26 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180273478-A1 | ANTI-CANCER COMPOUNDS | MKI67, TP53, CDK5 | HDAC1 88/4885HDAC8 133/4885HDAC6 53/4885 |
| US-10745355-B2 | Anti-cancer compounds | MKI67, TP53, CDK5 | HDAC1 88/4885HDAC8 133/4885HDAC6 53/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.