Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP8B1 | Q9UNU6 | 1/20 | 0.33 |
| ▸ | CKS1B | P61024 | 2/20 | 0.32 |
| ▸ | SKP1 | P63208 | 2/20 | 0.32 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.32 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.31 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.31 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4520769 | 0.84 | POLB (0.36) | MAPTCYP8B1POLB | |
| SCHEMBL203265 | 0.83 | TLR7 (0.39) | BACE1 | |
| SCHEMBL1233797 | 0.83 | CYP8B1 (0.38) | BACE1MAPTCYP8B1CKS1BSKP1 | |
| SCHEMBL203622 | 0.81 | BACE1 (0.33) | BACE1MAPTUSP30 | |
| SCHEMBL202535 | 0.71 | KMT2A (0.41) | MAPTCKS1BSKP1SKP2POLB | |
| SCHEMBL22075398 | 0.71 | UCHL1 (0.38) | MAPTCKS1BSKP1SKP2POLB | |
| SCHEMBL30074854 | 0.70 | HPGDS (0.43) | USP30EPHA2PIK3CDSCN9A | |
| SCHEMBL29036523 | 0.70 | HPGDS (0.43) | USP30PIK3CDSCN9A | |
| SCHEMBL30074832 | 0.70 | HPGDS (0.43) | USP30PIK3CDSCN9A | |
| SCHEMBL29036539 | 0.70 | HPGDS (0.43) | USP30EPHA2PIK3CDSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088788-B2 | Substituted fused[1,2] imidazo[4,5-c] ring compounds and methods | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-01-03 | — | — | US | disclosed |