SCHEMBL2050907

SCHEMBL2050907

O=C(O)c1cccc(OC(=O)c2cccc(C(=O)O)c2C(=O)O)c1C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.54
HSD17B10 Q99714 7/20 0.54
HPGD P15428 5/20 0.54
ALDH1A1 P00352 5/20 0.54
LMNA P02545 1/20 0.53
CYP1A2 P05177 1/20 0.53
CYP2C9 P11712 1/20 0.53
MAPK1 P28482 1/20 0.46
ESR1 P03372 4/20 0.46
TSHR P16473 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
ITGB3 P05106 1/20 0.46
ITGA2B P08514 1/20 0.46
HMGB1 P09429 1/20 0.46
GGT1 P19440 1/20 0.46
PTGS1 P23219 1/20 0.46
PTGS2 P35354 1/20 0.46
BLM P54132 1/20 0.46
NAPRT Q6XQN6 1/20 0.46
CA12 O43570 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalic Acid SCHEMBL2513148 0.91 KDM4E (0.57) KDM4EHSD17B10HPGDALDH1A1LMNA
SCHEMBL3655709 0.91 KDM4E (0.57) KDM4EHSD17B10HPGDALDH1A1LMNA
SCHEMBL11777918 0.86 SLC6A3 (0.58) KDM4EHSD17B10HPGDALDH1A1LMNA
SCHEMBL11196430 0.85 KDM4E (0.59) KDM4EHSD17B10HPGDALDH1A1LMNA
SCHEMBL11776239 0.85 ESR1 (0.58) KDM4EHSD17B10HPGDALDH1A1LMNA
SCHEMBL11432522 0.85 MAPK1 (0.49) KDM4EHSD17B10HPGDALDH1A1LMNA
SCHEMBL11269834 0.84 SLC6A3 (0.49) KDM4EHSD17B10HPGDALDH1A1LMNA
SCHEMBL10787362 0.82 ESR1 (0.48) KDM4EHSD17B10HPGDALDH1A1LMNA
SCHEMBL1156927 0.81 KDM4E (0.70) KDM4EHSD17B10HPGDALDH1A1LMNA
SCHEMBL28958206 0.80 KDM4E (0.43) KDM4EHSD17B10HPGDALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9095814-B2 Process for membrane separation of an olefin that is contained in a hydrocarbon mixture IFP Energies Nouvelles (FR) 2015-08-04 US disclosed
US-8506814-B2 Process for membrane separation of linear hydrocarbons within a hydrocarbon mixture IFP Energies Nouvelles (FR) 2013-08-13 US disclosed
US-8279378-B2 Producing method for lengthwise optical laminate and liquid crystal panel NITTO DENKO CORPORATION (JP) 2012-10-02 US disclosed
US-8174646-B2 Liquid crystal panel and liquid crystal display NITTO DENKO CORPORATION (JP) 2012-05-08 US disclosed
US-8021572-B2 Optical laminate, polarizing plate, image display, and process for producing an optical laminate NITTO DENKO CORPORATION (JP) 2011-09-20 US disclosed
US-20110130611-A1 PROCESS FOR MEMBRANE SEPARATION OF AN OLEFIN THAT IS CONTAINED IN A HYDROCARBON MIXTURE IFP Energies Nouvelles (FR) 2011-06-02 US disclosed
US-20100276368-A1 PROCESS FOR MEMBRANE SEPARATION OF LINEAR HYDROCARBONS WITHIN A HYDROCARBON MIXTURE IFP (FR) 2010-11-04 US disclosed
US-20100073608-A1 PRODUCING METHOD FOR LENGTHWISE OPTICAL LAMINATE AND LIQUID CRYSTAL PANEL NITTO DENKO CORPORATION (JP) 2010-03-25 US disclosed
US-20100067112-A1 OPTICAL LAMINATE, POLARIZING PLATE, IMAGE DISPLAY, AND PROCESS FOR PRODUCING AN OPTICAL LAMINATE NITTO DENKO CORPORATION (JP) 2010-03-18 US disclosed
US-20100060831-A1 LIQUID CRYSTAL PANEL AND LIQUID CRYSTAL DISPLAY NITTO DENKO CORPORATION (JP) 2010-03-11 US disclosed
US-7643118-B2 Liquid crystal panel and liquid crystal display device NITTO DENKO CORPORATION (JP) 2010-01-05 US disclosed
US-20090109385-A1 LIQUID CRYSTAL PANEL AND LIQUID CRYSTAL DISPLAY DEVICE NITTO DENKO CORPORATION (JP) 2009-04-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110130611-A1 PROCESS FOR MEMBRANE SEPARATION OF AN OLEFIN THAT IS CONTAINED IN A HYDROCARBON MIXTURE C9, PXMP4, FLOT1 KDM4E 4602/4885HSD17B10 706/4885HPGD 1246/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.