Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Ergocalciferol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR known ✓ | P11473 | 4/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 3/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 3/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | HSPD1 | P10809 | 2/20 | 1.00 |
| ▸ | PTGS1 | P23219 | 2/20 | 1.00 |
| ▸ | HSPE1 | P61604 | 2/20 | 1.00 |
| ▸ | ADRA1A | P35348 | 2/20 | 1.00 |
| ▸ | AR | P10275 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | USP2 | O75604 | 1/20 | 1.00 |
| ▸ | ABCB11 | O95342 | 1/20 | 1.00 |
| ▸ | ESR1 | P03372 | 1/20 | 1.00 |
| ▸ | TST | Q16762 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 4/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.71 |
| ▸ | PGR | P06401 | 3/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ergocalciferol SCHEMBL12346036 | 1.00 | ALDH1A1 (1.00) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| Ergocalciferol SCHEMBL3421 | 1.00 | ALDH1A1 (1.00) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| Ergocalciferol SCHEMBL12322071 | 1.00 | ALDH1A1 (1.00) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| Ergocalciferol SCHEMBL3228635 | 1.00 | ALDH1A1 (1.00) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| Ergocalciferol SCHEMBL24855744 | 1.00 | ALDH1A1 (1.00) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| Ergocalciferol SCHEMBL4140479 | 1.00 | ALDH1A1 (1.00) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| Ergocalciferol SCHEMBL24565106 | 1.00 | ALDH1A1 (1.00) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| Ergocalciferol SCHEMBL9980609 | 1.00 | ALDH1A1 (1.00) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| Ergocalciferol SCHEMBL3420 | 1.00 | ALDH1A1 (1.00) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| Ergocalciferol SCHEMBL10034120 | 1.00 | ALDH1A1 (1.00) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114397477-A | Flexible vitreous support element, Doppler differential interferometer and preparation method | 中国科学院西安光学精密机械研究所 | 2022-04-26 | — | — | CN | claimed |
| CN-112161611-B | In-plant concentricity positioning method for offshore wind power guide frame | 中铁大桥局集团第五工程有限公司 | 2022-03-18 | — | — | CN | claimed |
| CN-112161611-A | In-plant concentricity positioning method for offshore wind power guide frame | 中铁大桥局集团第五工程有限公司 | 2021-01-01 | — | — | CN | claimed |
| CN-117331266-A | High-precision secondary mirror focusing device of space deep low-temperature infrared camera | 北京空间机电研究所 | 2024-01-02 | — | — | CN | disclosed |
| CN-114778112-A | Audio identification and fault diagnosis method for mechanical fault of wind turbine generator system | 大唐（赤峰）新能源有限公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-114444123-A | Anonymous track privacy protection method based on semantic information | 湖南大学 | 2022-05-06 | — | — | CN | disclosed |
| CN-114397477-A | Flexible vitreous support element, Doppler differential interferometer and preparation method | 中国科学院西安光学精密机械研究所 | 2022-04-26 | — | — | CN | disclosed |
| CN-112161611-B | In-plant concentricity positioning method for offshore wind power guide frame | 中铁大桥局集团第五工程有限公司 | 2022-03-18 | — | — | CN | disclosed |
| US-20220041687-A1 | A GROUP OF CHIMERIC ANTIGEN RECEPTORS (CARS) | ST. ANNA KINDERKREBSFORSCHUNG (AT) | 2022-02-10 | — | — | US | disclosed |
| US-20210386781-A1 | A GROUP OF CHIMERIC ANTIGEN RECEPTORS (CARS) | UNIVERSITÄT FÜR BODENKULTUR WIEN (AT) | 2021-12-16 | — | — | US | disclosed |
| CN-113258838-B | System and method for adjusting spreading width of straw | 农业农村部南京农业机械化研究所 | 2021-10-01 | — | — | CN | disclosed |
| CN-111191374-A | Spacecraft attitude stability control real-time simulation verification and three-dimensional demonstration method | 天津大学 | 2020-05-22 | — | — | CN | disclosed |
| CN-111142096-A | Multi-base radar target positioning method based on grid division | 中国人民解放军国防科技大学 | 2020-05-12 | — | — | CN | disclosed |
| EP-3632461-A1 | A GROUP OF CHIMERIC ANTIGEN RECEPTORS (CARS) | St. Anna Kinderkrebsforschung (AT) | 2020-04-08 | — | — | EP | disclosed |
| EP-3632460-A1 | A GROUP OF CHIMERIC ANTIGEN RECEPTORS (CARS) | St. Anna Kinderkrebsforschung (AT) | 2020-04-08 | — | — | EP | disclosed |
| CN-110359831-A | Respond multiple sensor control motorized window articles | 路创技术有限责任公司 | 2019-10-22 | — | — | CN | disclosed |
| CN-106661918-B | Controlling motorized window treatments in response to multiple sensors | 路创技术有限责任公司 | 2019-08-27 | — | — | CN | disclosed |
| WO-2018175186-A1 | METHODS RELATING TO THE MEASUREMENT OF VITAMIN D AND VITAMIN D METABOLITES | TRUSTEES OF BOSTON UNIVERSITY (US) | 2018-09-27 | — | — | WO | disclosed |
| CN-106661918-A | Controlling motorized window treatments in response to multiple sensors | 卢特龙电子公司 | 2017-05-10 | — | — | CN | disclosed |
| CN-102302168-B | Vitamin d2 oil and preparation method thereof | SICHUAN NEIJIANG HUIXIN PHARMACEUTICAL CO LTD | 2012-09-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220041687-A1 | A GROUP OF CHIMERIC ANTIGEN RECEPTORS (CARS) | CARS1, CD74, HAVCR2 | VDR 2330/4885ALDH1A1 3325/4885ALOX15 4751/4885 |
| US-20210386781-A1 | A GROUP OF CHIMERIC ANTIGEN RECEPTORS (CARS) | CD74, HAVCR2, CD2BP2 | VDR 2330/4885ALDH1A1 4352/4885ALOX15 4824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.