Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.63 |
| ▸ | NPC1 | O15118 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2369006 | 0.81 | RAB9A (0.66) | RAB9ANPC1SMN1; SMN2CHEK1PKM | |
| SCHEMBL2368706 | 0.79 | RAB9A (0.97) | RAB9ANPC1SMN1; SMN2CHEK1PKM | |
| SCHEMBL2368821 | 0.73 | CHEK1 (1.00) | RAB9ANPC1SMN1; SMN2CHEK1PKM | |
| SCHEMBL20513932 | 0.73 | PDPK1 (0.40) | RAB9ANPC1SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL20514008 | 0.72 | HTT (0.55) | RAB9ANPC1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL2368460 | 0.70 | RAB9A (0.76) | RAB9ANPC1SMN1; SMN2CHEK1PKM | |
| SCHEMBL2368426 | 0.70 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2CHEK1PKM | |
| SCHEMBL2368692 | 0.70 | RAB9A (0.76) | RAB9ANPC1SMN1; SMN2CHEK1PKM | |
| SCHEMBL2369146 | 0.70 | GAA (1.00) | RAB9ANPC1SMN1; SMN2CHEK1PKM | |
| SCHEMBL3979882 | 0.69 | RAB9A (0.70) | RAB9ANPC1SMN1; SMN2CHEK1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107709334-B | Novel amino acid derivatives, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2021-04-13 | — | — | CN | disclosed |
| US-10457687-B2 | Aminoacid derivatives, a process for their preparation and pharmaceutical compositions containing them | LES LABORATOIRES SERVIER (FR) | 2019-10-29 | — | — | US | disclosed |
| US-20190031675-A1 | AMINOACID DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LES LABORATOIRES SERVIER (FR) | 2019-01-31 | — | — | US | disclosed |
| EP-3313850-B1 | NEW AMINOACID DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2018-10-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190031675-A1 | AMINOACID DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BAX, ARG2, ANXA5 | RAB9A 305/4885NPC1 2947/4885SMN1; SMN2 849/4885 |
| US-10457687-B2 | Aminoacid derivatives, a process for their preparation and pharmaceutical compositions containing them | BAX, ARG2, ANXA5 | RAB9A 305/4885NPC1 2947/4885SMN1; SMN2 849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.