Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31049278 | 0.82 | GPR84 (0.41) | GPR84HTR2A | |
| SCHEMBL5645619 | 0.80 | GPR84 (0.58) | GPR84HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL24214968 | 0.77 | GPR84 (0.38) | GPR84HTR2A | |
| SCHEMBL19629565 | 0.77 | NMT1 (0.34) | — | |
| SCHEMBL17518511 | 0.77 | AR (0.46) | GPR84HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL19629508 | 0.77 | EPRS1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL30233578 | 0.76 | GPR84 (0.37) | GPR84HTR2A | |
| Hydrochloric Acid SCHEMBL26658327 | 0.76 | GPR84 (0.37) | GPR84HTR2A | |
| SCHEMBL31714168 | 0.75 | DPYD (0.36) | — | |
| SCHEMBL25150835 | 0.75 | DPYD (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209654-B1 | NEW PYRAZOLE DERIVATIVES AS NIK INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-10-03 | — | — | EP | disclosed |