Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | CASP3 | P42574 | 2/20 | 0.33 |
| ▸ | CASP7 | P55210 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1659372 | 0.78 | HDAC3 (0.43) | HDAC3HDAC1MAPTLMNAALOX15 | |
| SCHEMBL1786039 | 0.73 | BLM (0.53) | MAPTLMNAALOX15ARALDH1A1 | |
| SCHEMBL1658749 | 0.73 | HDAC3 (0.56) | HDAC3HDAC1MAPTLMNAALOX15 | |
| SCHEMBL1658733 | 0.72 | MAPT (0.65) | MAPTMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1785875 | 0.71 | POLB (0.54) | LMNAHTTARALDH1A1KDM4E | |
| SCHEMBL1787253 | 0.71 | ATM (0.47) | MAPTTDP1ARALDH1A1L3MBTL1 | |
| SCHEMBL1658858 | 0.71 | ATM (0.52) | MAPTTDP1ALDH1A1L3MBTL1 | |
| SCHEMBL1658199 | 0.70 | HDAC1 (0.69) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL1660788 | 0.70 | ALDH1A1 (0.57) | MAPTTDP1LMNAMAPK1ALDH1A1 | |
| SCHEMBL16067271 | 0.70 | ALOX15 (0.41) | HDAC3HDAC1HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2262508-B1 | SUBSTITUTED-p-QUINONE DERIVATIVES FOR TREATMENT OF OXIDATIVE STRESS DISEASES | BIOELECTRON TECH CORP (US) | 2018-10-03 | — | — | EP | claimed |