Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 7/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.34 |
| ▸ | BRAF | P15056 | 2/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2052753 | 0.85 | GRIN2B (0.34) | GRIN2BGRIN1BRAFHSD17B1HSD17B2 | |
| SCHEMBL2051408 | 0.80 | MAPK14 (0.42) | GRIN2BBRAFALDH1A1 | |
| SCHEMBL13506674 | 0.80 | MEN1 (0.41) | — | |
| SCHEMBL2053541 | 0.79 | HSD17B1 (0.36) | GRIN2BBRAFHSD17B1HSD17B2ALDH1A1 | |
| SCHEMBL2050522 | 0.78 | BRAF (0.39) | GRIN2BBRAFHSD17B1HSD17B2ALDH1A1 | |
| SCHEMBL2053134 | 0.76 | PIK3C3 (0.46) | F10 | |
| SCHEMBL2051352 | 0.74 | MAPK13 (0.39) | BRAFHSD17B1HSD17B2TSHR | |
| SCHEMBL2053612 | 0.74 | GRIN2B (0.34) | GRIN2BHSD17B1HSD17B2ALDH1A1 | |
| SCHEMBL16105522 | 0.73 | CSNK1D (0.44) | PTGDR2 | |
| SCHEMBL2051404 | 0.73 | AAK1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110237588-A1 | Thienylpyri(mi)dinylazole | BAYER CROPSCIENCE AG (DE) | 2011-09-29 | — | — | US | disclosed |
| WO-2011076725-A1 | THIENYLPYRI (MI) DINYLAZOLE AND THEIR USE FOR CONTROLLING PHYTOPATHOGENIC FUNGI | BAYER CROPSCIENCE AG (DE) | 2011-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237588-A1 | Thienylpyri(mi)dinylazole | PADI1, TH, H1-3 | GRIN2B 2239/4885GRIN1 417/4885BRAF 3322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.