Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | APEX1 | P27695 | 2/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.39 |
| ▸ | ACLY | P53396 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6828217 | 0.86 | TDP1 (0.46) | TDP1MAPTALDH1A1KDM4EHSD17B10 | |
| SCHEMBL18529850 | 0.85 | TDP1 (0.52) | TDP1MAPTALDH1A1KDM4EHSD17B10 | |
| SCHEMBL6215307 | 0.83 | TDP1 (0.50) | TDP1MAPTALDH1A1KDM4EHSD17B10 | |
| SCHEMBL12756987 | 0.81 | TDP1 (0.49) | TDP1MAPTALDH1A1KDM4EHSD17B10 | |
| SCHEMBL1893739 | 0.81 | ALDH1A1 (0.56) | TDP1MAPTALDH1A1KDM4EHSD17B10 | |
| SCHEMBL1261447 | 0.81 | HMGCR (0.39) | ALDH1A1KDM4EHSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL18700959 | 0.81 | GAA (0.42) | MAPTALDH1A1KDM4EHSD17B10MRGPRX4 | |
| SCHEMBL23213504 | 0.80 | TDP1 (0.47) | TDP1MAPTALDH1A1KDM4EHSD17B10 | |
| SCHEMBL29947795 | 0.80 | TDP1 (0.47) | TDP1MAPTALDH1A1KDM4EHSD17B10 | |
| SCHEMBL288168 | 0.80 | TDP1 (0.47) | TDP1MAPTALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10365262-B2 | Method of monitoring a parameter of a hydrocarbon well, pipeline or formation | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2019-07-30 | — | — | US | disclosed |
| US-20180284096-A1 | METHOD OF MONITORING A PARAMETER OF A HYDROCARBON WELL, PIPELINE OR FORMATION | TRACERCO LIMITED (GB) | 2018-10-04 | — | — | US | disclosed |