Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | WDR5 | P61964 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23826927 | 0.92 | MAPT (0.52) | P2RY12L3MBTL1MAPTMAPK1HTT | |
| SCHEMBL17756947 | 0.87 | L3MBTL1 (0.51) | P2RY12L3MBTL1MAPTMAPK1PRMT1 | |
| SCHEMBL29902983 | 0.87 | KMT2A (0.52) | P2RY12L3MBTL1MAPTHTTMEN1 | |
| SCHEMBL10306695 | 0.87 | KMT2A (0.52) | P2RY12L3MBTL1MAPTHTTMEN1 | |
| SCHEMBL16528249 | 0.85 | L3MBTL1 (0.52) | P2RY12L3MBTL1MAPTMAPK1HTT | |
| SCHEMBL17756948 | 0.84 | L3MBTL1 (0.48) | P2RY12L3MBTL1MAPTMAPK1PRMT1 | |
| SCHEMBL20516395 | 0.84 | MEN1 (0.54) | L3MBTL1MAPTHTTMEN1KMT2A | |
| SCHEMBL20516367 | 0.84 | MEN1 (0.54) | MAPTHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL16527923 | 0.84 | L3MBTL1 (0.50) | P2RY12L3MBTL1MAPTMAPK1HTT | |
| SCHEMBL1742370 | 0.83 | SMN1; SMN2 (0.60) | MAPTMAPK1HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10336709-B2 | Lp-PLA2 inhibitors | ABIDE THERAPEUTICS, INC (US) | 2019-07-02 | — | — | US | disclosed |
| US-10336709-B2 | Lp-PLA2 inhibitors | ABIDE THERAPEUTICS, INC (US) | 2019-07-02 | — | — | US | disclosed |
| US-20180282288-A1 | LP-PLA2 INHIBITORS | H. LUNDBECK A/S (DK) | 2018-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180282288-A1 | LP-PLA2 INHIBITORS | PLA2G12A, PLA2G12B, PLA2G4B | P2RY12 441/4885L3MBTL1 3294/4885MAPT 4054/4885 |
| US-10336709-B2 | Lp-PLA2 inhibitors | PLA2G12A, PLA2G12B, PLA2G1B | P2RY12 423/4885L3MBTL1 2971/4885MAPT 4106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.