Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD2 | Q9HC29 | 1/20 | 1.00 |
| ▸ | ESR1 | P03372 | 2/20 | 0.68 |
| ▸ | PGR | P06401 | 2/20 | 0.68 |
| ▸ | HTR1A | P08908 | 1/20 | 0.68 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.68 |
| ▸ | AR | P10275 | 1/20 | 0.68 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.68 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.68 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.68 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.35 |
| ▸ | SELP | P16109 | 5/20 | 0.34 |
| ▸ | SELL | P14151 | 3/20 | 0.34 |
| ▸ | SELE | P16581 | 3/20 | 0.34 |
| ▸ | ANPEP | P15144 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Muramyldipeptide SCHEMBL20516503 | 1.00 | NOD2 (1.00) | NOD2ESR1PGRHTR1AADORA3 | |
| Muramyl Dipeptide SCHEMBL41813 | 1.00 | NOD2 (1.00) | NOD2ESR1PGRHTR1AADORA3 | |
| Muramyl Dipeptide SCHEMBL9770111 | 1.00 | NOD2 (1.00) | NOD2ESR1PGRHTR1AADORA3 | |
| Muramyldipeptide SCHEMBL15263102 | 1.00 | NOD2 (1.00) | NOD2ESR1PGRHTR1AADORA3 | |
| Muramyldipeptide SCHEMBL41814 | 1.00 | NOD2 (1.00) | NOD2ESR1PGRHTR1AADORA3 | |
| Muramyldipeptide SCHEMBL17299289 | 1.00 | NOD2 (1.00) | NOD2ESR1PGRHTR1AADORA3 | |
| Muramyldipeptide SCHEMBL19486934 | 1.00 | NOD2 (1.00) | NOD2ESR1PGRHTR1AADORA3 | |
| Muramyldipeptide SCHEMBL9231355 | 1.00 | NOD2 (1.00) | NOD2ESR1PGRHTR1AADORA3 | |
| Muramyl Dipeptide SCHEMBL769016 | 0.99 | NOD2 (0.98) | NOD2ESR1PGRHTR1AADORA3 | |
| SCHEMBL16802190 | 0.94 | NOD2 (0.88) | NOD2ESR1PGRHTR1AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250170237-A1 | MURAMYL DIPEPTIDES AND PROCESS FOR PREPARATION THEREOF | UNIVERSITEIT GENT (BE) | 2025-05-29 | — | — | US | disclosed |
| WO-2023161962-A1 | MURAMYL DIPEPTIDES AND PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2023-08-31 | — | — | WO | disclosed |
| US-11413299-B2 | Compositions and methods for treatment of inflammatory disorders | THE JOHNS HOPKINS UNIVERSITY (US) | 2022-08-16 | — | — | US | disclosed |
| US-20210128594-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF INFLAMMATORY DISORDERS | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2021-05-06 | — | — | US | disclosed |
| US-10668092-B2 | Compositions and methods for treatment of inflammatory disorders | THE JOHN HOPKINS UNIVERSITY (US) | 2020-06-02 | — | — | US | disclosed |
| US-20180280418-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF INFLAMMATORY DISORDERS | THE JOHNS HOPKINS UNIVERSITY | 2018-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180280418-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF INFLAMMATORY DISORDERS | TLR4, TLR3, TLR2 | NOD2 11/4885ESR1 1968/4885PGR 1666/4885 |
| US-10668092-B2 | Compositions and methods for treatment of inflammatory disorders | TLR4, TLR3, TLR2 | NOD2 11/4885ESR1 1968/4885PGR 1666/4885 |
| US-11413299-B2 | Compositions and methods for treatment of inflammatory disorders | TLR4, TLR3, TLR2 | NOD2 11/4885ESR1 1968/4885PGR 1666/4885 |
| US-20210128594-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF INFLAMMATORY DISORDERS | TLR4, TLR3, TLR2 | NOD2 11/4885ESR1 1968/4885PGR 1666/4885 |
| US-20250170237-A1 | MURAMYL DIPEPTIDES AND PROCESS FOR PREPARATION THEREOF | NOD2, NOD1, TLR9 | NOD2 1/4885ESR1 4554/4885PGR 4772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.