Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2051661 | 1.00 | LMNA (0.34) | LMNAMAPK1HTTL3MBTL1CES2 | |
| SCHEMBL2047095 | 0.87 | LMNA (0.33) | LMNAMAPK1HTTL3MBTL1 | |
| SCHEMBL2047093 | 0.87 | LMNA (0.33) | LMNAMAPK1HTTL3MBTL1 | |
| SCHEMBL9899557 | 0.83 | CES2 (0.44) | LMNAMAPK1L3MBTL1CES2CES1 | |
| SCHEMBL9899556 | 0.83 | CES2 (0.44) | LMNAMAPK1L3MBTL1CES2CES1 | |
| SCHEMBL2048180 | 0.81 | LMNA (0.35) | LMNAMAPK1HTTL3MBTL1CES2 | |
| SCHEMBL2048184 | 0.81 | LMNA (0.35) | LMNAMAPK1HTTL3MBTL1CES2 | |
| SCHEMBL2050499 | 0.80 | ATM (0.35) | LMNAMAPK1HTTL3MBTL1CES2 | |
| SCHEMBL2050501 | 0.80 | ATM (0.35) | LMNAMAPK1HTTL3MBTL1CES2 | |
| SCHEMBL9898927 | 0.76 | CES2 (0.38) | LMNAMAPK1HTTL3MBTL1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2516475-B1 | POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE | BRIDGESTONE CORP (JP) | 2020-10-07 | — | — | EP | claimed |
| US-8338544-B2 | Polymers functionalized with polyoxime compounds and methods for their manufacture | BRIDGESTONE CORPORATION (JP) | 2012-12-25 | — | — | US | claimed |
| EP-2516475-A1 | POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE | Bridgestone Corporation (JP) | 2012-10-31 | — | — | EP | claimed |
| US-20110152449-A1 | POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE | BRIDGESTONE CORPORATION (JP) | 2011-06-23 | — | — | US | claimed |
| EP-2516475-B1 | POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE | BRIDGESTONE CORP (JP) | 2020-10-07 | — | — | EP | disclosed |
| US-8338544-B2 | Polymers functionalized with polyoxime compounds and methods for their manufacture | BRIDGESTONE CORPORATION (JP) | 2012-12-25 | — | — | US | disclosed |
| EP-2516475-A1 | POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE | Bridgestone Corporation (JP) | 2012-10-31 | — | — | EP | disclosed |
| US-20110152449-A1 | POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE | BRIDGESTONE CORPORATION (JP) | 2011-06-23 | — | — | US | disclosed |