SCHEMBL2051982

SCHEMBL2051982

CN1CC(=O)Cc2ccccc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.48
NOTUM Q6P988 2/20 0.44
HPGD P15428 2/20 0.43
BRD4 O60885 1/20 0.43
CREBBP Q92793 1/20 0.43
CYP2A6 P11509 1/20 0.42
CASP3 P42574 2/20 0.40
CASP6 P55212 2/20 0.40
SENP8 Q96LD8 2/20 0.40
SENP7 Q9BQF6 2/20 0.40
SENP6 Q9GZR1 2/20 0.40
KMT2A Q03164 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
HTR7 P34969 5/20 0.40
CHRNB4 P30926 1/20 0.40
CHRNA3 P32297 1/20 0.40
ALDH1A1 P00352 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HTR1A P08908 2/20 0.38
GAA P10253 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22541020 0.81 CYP2A6 (0.48) CYP1A2NOTUMHPGDCYP2A6KMT2A
SCHEMBL2616329 0.79 DRD3 (0.48) CYP1A2NOTUMHPGDBRD4CREBBP
SCHEMBL10460338 0.79 CYP1A2 (0.58) CYP1A2NOTUMHPGDCYP2A6CASP3
SCHEMBL18034998 0.78
SCHEMBL14514477 0.77 CYP1A2 (0.45) CYP1A2NOTUMHPGDCYP2A6CASP3
SCHEMBL16844666 0.76 ALDH1A1 (0.38) CYP1A2NOTUMHPGDBRD4CREBBP
SCHEMBL27994929 0.76 CYP1A2 (0.48) CYP1A2NOTUMHPGDCYP2A6KMT2A
SCHEMBL5022144 0.76 HSD17B10 (0.44) NOTUMHPGDKMT2AALDH1A1SMN1; SMN2
SCHEMBL19224526 0.74 CYP1A2 (0.52) CYP1A2NOTUMHPGDBRD4CYP2A6
SCHEMBL6362412 0.73 HPGD (0.53) CYP1A2NOTUMHPGDCYP2A6KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1317013-B1 NON-AQUEOUS ELECTROLYTE AND SECONDARY CELL USING THE SAME MITSUBISHI CHEM CORP (JP) 2017-03-15 EP disclosed
US-20120101082-A1 VASOPRESSIN V1A ANTAGONISTS BATT ANDRZEJ ROMAN (GB) 2012-04-26 US disclosed
US-7964691-B2 5,5-diallyl-2,2-dimethyl-1,3-dioxane as monomer units; polymerization catalysts; heat resistance SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-06-21 US disclosed
WO-2009038006-A1 RANDOM COPOLYMER AND PRODUCTION PROCESS THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-03-26 WO disclosed
WO-2009038031-A1 BLOCK COPOLYMER AND PRODUCTION PROCESS THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-03-26 WO disclosed
US-20080214755-A1 OLEFIN-DIENE COPOLYMER AND PROCESS FOR PRODUCING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-04 US disclosed
US-7214677-B2 Benzamide, heteroarylamide and reverse amides PFIZER INC. (US) 2007-05-08 US disclosed
US-20070021509-A1 Phosphate transport inhibitors JOZEFIAK THOMAS H 2007-01-25 US disclosed
US-6942948-B2 Nonaqueous electrolyte solution and secondary battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2005-09-13 US disclosed
CN-1215595-C Nonaqueous electrolyte and secondary battery using the same MITSUBISHI CHEM CORP (JP) 2005-08-17 CN disclosed
CN-1465117-A Nonaqueous electrolyte and secondary battery using the same MITSUBISHI CHEM CORP (JP) 2003-12-31 CN disclosed
US-20030165733-A1 Nonaqueous electrolyte solution and secondary battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2003-09-04 US disclosed
EP-1317013-A1 NON-AQUEOUS ELECTROLYTE AND SECONDARY CELL USING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2003-06-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120101082-A1 VASOPRESSIN V1A ANTAGONISTS AVPR1A, AVPR2, AVPR1B CYP1A2 1224/4885NOTUM 4208/4885HPGD 286/4885
US-20070021509-A1 Phosphate transport inhibitors SLC34A2, SLC34A1, SLC20A1 CYP1A2 617/4885NOTUM 2402/4885HPGD 913/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.