Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.48 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.47 |
| ▸ | ACP3 | P15309 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CASR | P41180 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.44 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29914128 | 1.00 | TDP1 (0.56) | TDP1CYP1A2KDM4EALDH1A1HSD17B10 | |
| SCHEMBL27647542 | 0.86 | TDP1 (0.51) | TDP1CYP1A2KDM4ESSTR4CTNNB1 | |
| SCHEMBL7824528 | 0.86 | TDP1 (0.56) | TDP1CYP1A2KDM4EALDH1A1HSD17B10 | |
| SCHEMBL7287681 | 0.85 | TDP1 (0.54) | TDP1CYP1A2KDM4EALDH1A1HSD17B10 | |
| SCHEMBL7317433 | 0.84 | TDP1 (0.61) | TDP1CYP1A2KDM4EALDH1A1HSD17B10 | |
| SCHEMBL6531713 | 0.83 | TDP1 (0.53) | TDP1CYP1A2KDM4EALDH1A1HSD17B10 | |
| SCHEMBL17698876 | 0.83 | WDR5 (0.46) | TDP1CYP1A2KDM4EALDH1A1HSD17B10 | |
| SCHEMBL29981949 | 0.83 | TDP1 (0.53) | TDP1CYP1A2KDM4EALDH1A1HSD17B10 | |
| SCHEMBL15983796 | 0.83 | LMNA (0.49) | CYP1A2KDM4EKMT2AMAPTCYP2C19 | |
| SCHEMBL808870 | 0.82 | TDP1 (0.53) | TDP1CYP1A2SSTR4CTNNB1ACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180282165-A1 | METHOD OF FORMING A MULTILAYER STRUCTURE | ROHM & HAAS ELECT MAT (US) | 2018-10-04 | — | — | US | disclosed |