SCHEMBL2052097

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28456343	0.76	TAAR1 (0.66)	PAK4IRAK4MAPTGAALRRK2
	SCHEMBL14547925	0.76	PAK4 (0.57)	PTK2PAK4JAK1IRAK4TTK
	SCHEMBL20776757	0.73	PTK2 (1.00)	PTK2GRK5EGFRGAABTK
	SCHEMBL14547919	0.72	LRRK2 (0.70)	PTK2GRK5PAK4JAK1IRAK4
	SCHEMBL28452246	0.72	PAK4 (0.51)	PTK2GRK5PAK4JAK1IRAK4
	SCHEMBL28374655	0.71	JAK2 (0.57)	PTK2JAK2
	SCHEMBL15102600	0.70	ADORA3 (0.59)	JAK3EGFRMAPTGAAMEN1
	SCHEMBL14547770	0.70	PTK2 (0.53)	PTK2GRK5PAK4JAK3MAPT
	SCHEMBL28612718	0.69	PTK2 (0.81)	PTK2GRK5MEN1KMT2A
	SCHEMBL14287378	0.69	LRRK2 (0.69)	PTK2GRK5PAK4JAK3LRRK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.