SCHEMBL2052229

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2047804	0.94	LMNA (0.45)	ALDH1A1LMNAMAPTHTTMAPK1
	SCHEMBL2049794	0.89	LMNA (0.43)	ALDH1A1LMNAMAPTHTTMAPK1
	SCHEMBL2050081	0.86	DHODH (0.42)	ALDH1A1LMNAMAPTHTTMAPK1
	SCHEMBL2050291	0.85	POLB (0.40)	ALDH1A1LMNAHTTKEAP1NFE2L2
	SCHEMBL2050581	0.85	P2RY1 (0.41)	ALDH1A1LMNAMAPTHTTMAPK1
	SCHEMBL2049810	0.85	KMT2A (0.47)	ALDH1A1LMNAMAPTMAPK1KEAP1
	SCHEMBL2050508	0.85	SCN9A (0.42)	ALDH1A1LMNAMAPTMAPK1KEAP1
	SCHEMBL2046304	0.85	KMT2A (0.42)	ALDH1A1LMNAMAPTHTTMAPK1
	SCHEMBL2050269	0.83	KMT2A (0.41)	ALDH1A1LMNAMAPTMAPK1KEAP1
	SCHEMBL2044267	0.83	HTR6 (0.50)	ALDH1A1LMNAMAPTMAPK1KEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.