SCHEMBL20522384

SCHEMBL20522384

Fc1ccc(-c2ncccc2NCc2ccc3[nH]cnc3c2)cc1

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
QPCT Q16769 3/20 0.45
KDR P35968 3/20 0.42
SHMT2 P34897 1/20 0.41
RPS6KB1 P23443 1/20 0.39
ADORA2A P29274 1/20 0.39
ADORA2B P29275 1/20 0.39
ADORA1 P30542 1/20 0.39
NAMPT P43490 2/20 0.39
BACE1 P56817 1/20 0.39
KDM4E B2RXH2 1/20 0.38
MERTK Q12866 1/20 0.38
GPR55 Q9Y2T6 1/20 0.37
GRM4 Q14833 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29550847 1.00 QPCT (0.45) QPCTKDRSHMT2RPS6KB1ADORA2A
SCHEMBL29551454 0.86 KDR (0.45) QPCTKDRBACE1KDM4E
SCHEMBL20522328 0.86 KDR (0.45) QPCTKDRBACE1KDM4E
SCHEMBL20522358 0.84 QPCT (0.47) QPCTKDRSHMT2NAMPTKDM4E
SCHEMBL29550383 0.84 QPCT (0.47) QPCTKDRSHMT2NAMPTKDM4E
SCHEMBL20522432 0.84 QPCT (0.47) QPCTKDRSHMT2NAMPT
SCHEMBL29550580 0.84 QPCT (0.47) QPCTKDRSHMT2NAMPT
SCHEMBL20522411 0.82 QPCT (0.45) QPCTKDRSHMT2ADORA2AADORA2B
SCHEMBL22712387 0.82 QPCT (0.45) QPCTKDRKDM4EGRM4
SCHEMBL29550630 0.82 QPCT (0.45) QPCTKDRKDM4EGRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110719910-B Novel inhibitors 维沃里翁治疗股份有限公司 2023-07-21 CN claimed
US-11339152-B2 Inhibitors VIVORYON THERAPEUTICS N.V. 2022-05-24 US claimed
US-20200377493-A1 NOVEL INHIBITORS VIVORYON THERAPEUTICS N.V. (DE) 2020-12-03 US claimed
EP-3601269-A1 NOVEL INHIBITORS Probiodrug AG (DE) 2020-02-05 EP claimed
WO-2018178384-A1 NOVEL INHIBITORS PROBIODRUG AG (DE) 2018-10-04 WO claimed
US-20260001873-A1 NOVEL INHIBITORS VIVORYON THERAPEUTICS N.V. (DE) 2026-01-01 US disclosed
US-12384772-B2 Inhibitors VIVORYON THERAPEUTICS N.V. (DE) 2025-08-12 US disclosed
CN-117024352-A Novel inhibitors 维沃里翁治疗股份有限公司 2023-11-10 CN disclosed
CN-110719910-B Novel inhibitors 维沃里翁治疗股份有限公司 2023-07-21 CN disclosed
US-20220274977-A1 NOVEL INHIBITORS VIVORYON THERAPEUTICS N.V. (DE) 2022-09-01 US disclosed
US-11339152-B2 Inhibitors VIVORYON THERAPEUTICS N.V. 2022-05-24 US disclosed
US-11339152-B2 Inhibitors VIVORYON THERAPEUTICS N.V. 2022-05-24 US disclosed
US-20200377493-A1 NOVEL INHIBITORS VIVORYON THERAPEUTICS N.V. (DE) 2020-12-03 US disclosed
US-20200377493-A1 NOVEL INHIBITORS VIVORYON THERAPEUTICS N.V. (DE) 2020-12-03 US disclosed
EP-3601269-A1 NOVEL INHIBITORS Probiodrug AG (DE) 2020-02-05 EP disclosed
WO-2018178384-A1 NOVEL INHIBITORS PROBIODRUG AG (DE) 2018-10-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260001873-A1 NOVEL INHIBITORS GLS, GLS2, SULT1E1 QPCT 6/4885KDR 2611/4885SHMT2 535/4885
US-20200377493-A1 NOVEL INHIBITORS GLUL, GLS, QPCT QPCT 3/4885KDR 2432/4885SHMT2 571/4885
US-11339152-B2 Inhibitors GLUL, QPCT, GLS QPCT 2/4885KDR 2483/4885SHMT2 512/4885
US-12384772-B2 Inhibitors GLS, QPCT, GLS2 QPCT 2/4885KDR 2197/4885SHMT2 515/4885
US-20220274977-A1 NOVEL INHIBITORS GLUL, GLS, QPCT QPCT 3/4885KDR 2829/4885SHMT2 590/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.