Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | PPARA | Q07869 | 4/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | PRMT3 | O60678 | 2/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.40 |
| ▸ | PRMT8 | Q9NR22 | 2/20 | 0.40 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21708289 | 0.79 | ALDH1A1 (0.49) | ALDH1A1HSD17B10KMT2AMAP4K4PARP10 | |
| SCHEMBL395088 | 0.79 | ABL1 (0.60) | ALDH1A1HSD17B10KMT2AL3MBTL1ADORA3 | |
| SCHEMBL1270983 | 0.78 | ALDH1A1 (0.62) | ALDH1A1HSD17B10KMT2AL3MBTL1ADORA3 | |
| SCHEMBL28698396 | 0.78 | KMT2A (0.47) | KMT2AMAP4K4BTKPPARGPPARA | |
| SCHEMBL6480845 | 0.77 | ALDH1A1 (0.83) | ALDH1A1HSD17B10L3MBTL1ADORA3GAA | |
| SCHEMBL16847542 | 0.76 | ALDH1A1 (0.60) | ALDH1A1HSD17B10L3MBTL1ADORA3GAA | |
| SCHEMBL624800 | 0.76 | MAP4K4 (0.55) | KMT2AMAP4K4BTKPARP10PRMT3 | |
| SCHEMBL4178299 | 0.76 | GAA (0.62) | ALDH1A1KMT2APPARGPPARAPTPN5 | |
| SCHEMBL13271315 | 0.75 | PPARG (0.68) | KMT2APPARGPPARABRD4CREBBP | |
| SCHEMBL31264295 | 0.75 | ALDH1A1 (0.79) | ALDH1A1HSD17B10KMT2AL3MBTL1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110719910-A | Novel inhibitors | 前体生物药物股份公司 | 2020-01-21 | — | — | CN | claimed |
| CN-117024352-A | Novel inhibitors | 维沃里翁治疗股份有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-110719910-B | Novel inhibitors | 维沃里翁治疗股份有限公司 | 2023-07-21 | — | — | CN | disclosed |
| EP-3601269-A1 | NOVEL INHIBITORS | Probiodrug AG (DE) | 2020-02-05 | — | — | EP | disclosed |
| CN-110719910-A | Novel inhibitors | 前体生物药物股份公司 | 2020-01-21 | — | — | CN | disclosed |
| WO-2018178384-A1 | NOVEL INHIBITORS | PROBIODRUG AG (DE) | 2018-10-04 | — | — | WO | disclosed |
| CN-103980618-A | Mono-and multi-layer blown films | BASF SE | 2014-08-13 | — | — | CN | disclosed |
| CN-101018843-B | Alkylaminoacetamide lubricant additives | CIBA SC HOLDING AG | 2011-05-11 | — | — | CN | disclosed |
| CN-101815698-A | Degradation promoters for polymers and polymeric articles containing the same | CIBA HOLDING INC | 2010-08-25 | — | — | CN | disclosed |
| CN-101018821-B | Polyolefin articles | CIBA SC HOLDING AG | 2010-06-16 | — | — | CN | disclosed |
| CN-100516155-C | Coating compositions comprising leveling agents prepared by nitroxyl-mediated polymerization | CIBA SC HOLDING AG (CH) | 2009-07-22 | — | — | CN | disclosed |
| CN-101258194-A | A degradable polymer article | CIBA HOLDING INC (CH) | 2008-09-03 | — | — | CN | disclosed |
| CN-101018843-A | Alkylaminoacetamide lubricant additives | CIBA SC HOLDING AG (CH) | 2007-08-15 | — | — | CN | disclosed |
| CN-101018821-A | Polyolefin articles | CIBA SC HOLDING AG (CH) | 2007-08-15 | — | — | CN | disclosed |
| CN-1890335-A | Coating compositions comprising leveling agents prepared by nitroxyl-mediated polymerization | CIBA SC HOLDING AG (CH) | 2007-01-03 | — | — | CN | disclosed |