SCHEMBL6480845

SCHEMBL6480845

Nc1ccccc1-c1ccc(-c2ccccc2N)cc1

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.83
HSD17B10 Q99714 2/20 0.83
L3MBTL1 Q9Y468 1/20 0.71
SMN1; SMN2 Q16637 2/20 0.53
CYP3A4 P08684 2/20 0.53
ALOX15 P16050 2/20 0.53
CASP1 P29466 1/20 0.53
CASP7 P55210 1/20 0.53
DHFR P00374 1/20 0.47
KDM4E B2RXH2 1/20 0.47
NPC1 O15118 1/20 0.47
GAA P10253 1/20 0.47
HPGD P15428 1/20 0.47
RAB9A P51151 1/20 0.47
BCHE P06276 1/20 0.44
ACHE P22303 1/20 0.44
HDAC3 O15379 1/20 0.43
HDAC4 P56524 1/20 0.43
HDAC1 Q13547 1/20 0.43
HDAC7 Q8WUI4 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31264295 0.97 ALDH1A1 (0.79) ALDH1A1HSD17B10L3MBTL1SMN1; SMN2CYP3A4
SCHEMBL712916 0.92 ALDH1A1 (0.90) ALDH1A1HSD17B10L3MBTL1SMN1; SMN2CYP3A4
SCHEMBL29510158 0.92 ALDH1A1 (0.71) ALDH1A1HSD17B10L3MBTL1SMN1; SMN2CYP3A4
SCHEMBL599657 0.92 ALDH1A1 (0.71) ALDH1A1HSD17B10L3MBTL1SMN1; SMN2CYP3A4
SCHEMBL28465796 0.91 ALDH1A1 (1.00) ALDH1A1HSD17B10L3MBTL1SMN1; SMN2CYP3A4
SCHEMBL27950997 0.91 ALDH1A1 (1.00) ALDH1A1HSD17B10L3MBTL1SMN1; SMN2CYP3A4
SCHEMBL25981 0.91 ALDH1A1 (1.00) ALDH1A1HSD17B10L3MBTL1SMN1; SMN2CYP3A4
Benzene SCHEMBL28328298 0.91 ALDH1A1 (1.00) ALDH1A1HSD17B10L3MBTL1SMN1; SMN2CYP3A4
SCHEMBL29407079 0.91 ALDH1A1 (1.00) ALDH1A1HSD17B10L3MBTL1SMN1; SMN2CYP3A4
SCHEMBL27787239 0.91 ALDH1A1 (0.89) ALDH1A1HSD17B10L3MBTL1SMN1; SMN2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117820776-A Polymer-based composite material with low dielectric constant and low dielectric loss, and preparation method and application thereof 四川大学 2024-04-05 CN claimed
US-9296862-B2 Preparation of poly(octatriazacane) INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2016-03-29 US claimed
WO-2015195686-A1 PREPARATION OF POLY(OCTATRIAZACANE) INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2015-12-23 WO claimed
US-20150361220-A1 PREPARATION OF POLY(OCTATRIAZACANE) INTERNATIONAL BUSINESS MACHINES CORPORATION 2015-12-17 US claimed
CN-117820776-A Polymer-based composite material with low dielectric constant and low dielectric loss, and preparation method and application thereof 四川大学 2024-04-05 CN disclosed
EP-3671885-B1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO LTD (JP) 2023-03-01 EP disclosed
EP-3877373-B1 5,6-DIPHENYL-5,6-DIHYDRO-DIBENZ[C,E][1,2]AZAPHOSPHORINE AND 6-PHENYL-6H-DIBENZO[C,E][1,2]THIAZINE-5,5-DIOXIDE DERIVATIVES AND RELATED COMPOUNDS AS ORGANIC ELECTROLUMINESCENT MATERIALS FOR OLEDS MERCK PATENT GMBH (DE) 2023-01-11 EP disclosed
CN-115461381-A Acid group-containing (meth) acrylate resin, curable resin composition, insulating material, resin material for solder resist, and resist member DIC株式会社 2022-12-09 CN disclosed
EP-3244464-B1 ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2022-02-23 EP disclosed
US-20220020934-A1 5,6-DIPHENYL-5,6-DIHYDRO-DIBENZ[C,E][1,2]AZAPHOSPHORIN AND 6-PHENYL-6H-DIBENZO[C,E][1,2]THIAZIN-5,5-DIOXIDE DERIVATIVES AND SIMILAR COMPOUNDS AS ORGANIC ELECTROLUMINESCENT MATERIALS FOR OLEDS MERCK PATENT GMBH (DE) 2022-01-20 US disclosed
EP-3355376-B1 ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2021-12-01 EP disclosed
US-10950797-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2021-03-16 US disclosed
US-9166176-B2 Polycyclic aromatic compound KYOTO UNIVERSITY (JP) 2015-10-20 US disclosed
US-20150097162-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE JNC CORPORATION (JP) 2015-04-09 US disclosed
US-8728431-B2 Method of preparing carbon nanotubes and catalyst for producing carbon nanotubes TOKYO OHKA KOGYO CO., LTD. (JP) 2014-05-20 US disclosed
US-20130040107-A1 METHOD FOR PRODUCING SUBSTRATE HAVING DISPERSED PARTICLES OF DENDRIMER COMPOUND ON THE SURFACE THEREOF, AND SUBSTRATE HAVING DISPERSED PARTICLES OF DENDRIMER COMPOUND ON THE SURFACE THEREOF TOKYO INSTITUTE OF TECHNOLOGY (JP) 2013-02-14 US disclosed
US-20120308470-A1 METHOD OF PREPARING CARBON NANOTUBES AND CATALYST FOR PRODUCING CARBON NANOTUBES TOKYO INSTITUTE OF TECHNOLOGY (JP) 2012-12-06 US disclosed
WO-2012076886-A2 NOVEL PROCESS AND COMPOUNDS THE UNIVERSITY OF MANCHESTER (GB) 2012-06-14 WO disclosed
US-6846563-B2 Sizing composition for glass yarns, method using said composition and resulting products SAINT-GOBAIN VETROTEX FRANCE S.A. (FR) 2005-01-25 US disclosed
US-20030194553-A1 Sizing composition for glass yarns, method using composition and resulting products OCV INTELLECTUAL CAPITAL, LLC 2003-10-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220020934-A1 5,6-DIPHENYL-5,6-DIHYDRO-DIBENZ[C,E][1,2]AZAPHOSPHORIN AND 6-PHENYL-6H-DIBENZO[C,E][1,2]THIAZIN-5,5-DIOXIDE DERIVATIVES AND SIMILAR COMPOUNDS AS ORGANIC ELECTROLUMINESCENT MATERIALS FOR OLEDS AZI2, OCIAD2, SELP ALDH1A1 1049/4885HSD17B10 2681/4885L3MBTL1 3961/4885
US-10950797-B2 Organic electroluminescent device SLC29A2, SLC29A1, NUDT1 ALDH1A1 427/4885HSD17B10 1899/4885L3MBTL1 984/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.