SCHEMBL2052255

SCHEMBL2052255

Cc1nncc(-c2c(F)cccc2F)c1-c1ccc(Cl)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.42
NPC1 O15118 3/20 0.42
CASP3 P42574 1/20 0.42
SENP8 Q96LD8 1/20 0.42
SENP7 Q9BQF6 1/20 0.42
SENP6 Q9GZR1 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
PDE2A O00408 1/20 0.37
PDE10A Q9Y233 1/20 0.37
GABRA1 P14867 1/20 0.37
GABRG2 P18507 1/20 0.37
GABRB3 P28472 1/20 0.37
GABRA5 P31644 1/20 0.37
GABRA3 P34903 1/20 0.37
APEX1 P27695 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23012578 0.86 MAOB (0.39) RAB9ANPC1CASP3SENP8SENP7
SCHEMBL68893 0.80 NPC1 (0.47) RAB9ANPC1CASP3SENP8SENP7
SCHEMBL13165378 0.77 APEX1 (0.48) RAB9ANPC1CASP3SENP8SENP7
SCHEMBL3311845 0.77 NPC1 (0.42) RAB9ANPC1CASP3SENP8SENP7
SCHEMBL29369509 0.76 NPC1 (0.44) RAB9ANPC1CASP3SENP8SENP7
SCHEMBL13165374 0.76 NPC1 (0.44) RAB9ANPC1CASP3SENP8SENP7
SCHEMBL27981989 0.76 NPC1 (0.44) RAB9ANPC1CASP3SENP8SENP7
SCHEMBL69222 0.76 NPC1 (0.44) RAB9ANPC1CASP3SENP8SENP7
SCHEMBL19328777 0.75 GABRG2 (0.39) RAB9ANPC1CASP3SENP8SENP7
SCHEMBL2888290 0.75 NPC1 (0.43) RAB9ANPC1CASP3SENP8SENP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011076726-A2 PESTICIDAL COMPOUND MIXTURES BAYER CROPSCIENCE AG (DE) 2011-06-30 WO claimed
CN-109561676-A The pyrrolidones that N- replaces is used to promote the purposes of the infiltration of agrochemical active ingredient 科莱恩国际有限公司 2019-04-02 CN disclosed
EP-2170044-A1 POLYMER COMPOSITE MATERIAL WITH BIOCIDE FUNCTIONALITY Bayer Innovation GmbH (DE) 2010-04-07 EP disclosed
WO-2009012887-A1 POLYMER COMPOSITE MATERIAL WITH BIOCIDE FUNCTIONALITY BAYER INNOVATION GMBH (DE) 2009-01-29 WO disclosed