SCHEMBL68893

SCHEMBL68893

Cc1nnc(C)c(-c2c(F)cccc2F)c1-c1ccc(Cl)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.47
RAB9A P51151 3/20 0.47
CASP3 P42574 1/20 0.47
SENP8 Q96LD8 1/20 0.47
SENP7 Q9BQF6 1/20 0.47
SENP6 Q9GZR1 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
PDE2A O00408 2/20 0.41
PDE10A Q9Y233 2/20 0.41
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
APEX1 P27695 1/20 0.38
IKBKB O14920 1/20 0.37
MAP3K14 Q99558 1/20 0.37
TTR P02766 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2888290 0.94 NPC1 (0.43) NPC1RAB9ACASP3SENP8SENP7
SCHEMBL29369509 0.92 NPC1 (0.44) NPC1RAB9ACASP3SENP8SENP7
SCHEMBL13165374 0.92 NPC1 (0.44) NPC1RAB9ACASP3SENP8SENP7
SCHEMBL69222 0.92 NPC1 (0.44) NPC1RAB9ACASP3SENP8SENP7
SCHEMBL3311845 0.86 NPC1 (0.42) NPC1RAB9ACASP3SENP8SENP7
SCHEMBL3971627 0.85 RAB9A (0.39) NPC1RAB9ACASP3SENP8SENP7
SCHEMBL2348112 0.85 NPC1 (0.41) NPC1RAB9ACASP3SENP8SENP7
SCHEMBL10015955 0.84 MAOB (0.47) L3MBTL1CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL13165378 0.83 APEX1 (0.48) NPC1RAB9ACASP3SENP8SENP7
SCHEMBL8531419 0.82 NPC1 (0.44) NPC1RAB9ACASP3SENP8SENP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2566 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4384016-B1 ACTIVE COMPOUND COMBINATIONS AND FUNGICIDE COMPOSITIONS COMPRISING THOSE BAYER AG (DE) 2025-09-03 EP claimed
WO-2025098874-A1 ACTIVE COMPOUND COMBINATIONS HAVING FUNGICIDAL/INSECTICIDAL/ACARICIDAL PROPERTIES BAYER AKTIENGESELLSCHAFT (DE) 2025-05-15 WO claimed
US-20240365785-A1 ACTIVE COMPOUND COMBINATIONS AND FUNGICIDE COMPOSITIONS COMPRISING THOSE BAYER AKTIENGESELLSCHAFT (DE) 2024-11-07 US claimed
EP-4384016-A1 ACTIVE COMPOUND COMBINATIONS AND FUNGICIDE COMPOSITIONS COMPRISING THOSE Bayer Aktiengesellschaft (DE) 2024-06-19 EP claimed
CN-118102874-A Active compound combinations and fungicide compositions comprising them 拜耳公司 2024-05-28 CN claimed
US-20240016152-A1 ACTIVE COMPOUND COMBINATIONS BAYER AKTIENGESELLSCHAFT (DE) 2024-01-18 US claimed
US-20230413824-A1 AGROCHEMICAL COMPOSITION COMPRISING 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS AND USE THEREOF PI INDUSTRIES LTD. (IN) 2023-12-28 US claimed
EP-4250926-A1 AGROCHEMICAL COMPOSITION COMPRISING 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS AND USE THEREOF PI Industries Ltd. (IN) 2023-10-04 EP claimed
CN-116801720-A Novel agrochemical compositions comprising 3-substituted benzamidine compounds and uses thereof 皮埃企业有限公司 2023-09-22 CN claimed
US-20230276803-A1 A PESTICIDALLY ACTIVE MIXTURE COMPRISING THIETANYLOXY COMPOUND, OXIDES OR SALTS THEREOF PI INDUSTRIES LTD. (IN) 2023-09-07 US claimed
WO-2009090181-A2 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE BAYER CROPSCIENCE SA (FR) 2009-07-23 WO claimed
EP-2014165-A1 Active compound combinations Bayer CropScience AG (DE) 2009-01-14 EP claimed
EP-2014167-A1 Active compound combinations Bayer CropScience AG (DE) 2009-01-14 EP claimed
EP-2014166-A1 Active compound combinations Bayer CropScience AG (DE) 2009-01-14 EP claimed
EP-2011396-A1 Active compound combinations Bayer CropScience AG (DE) 2009-01-07 EP claimed
EP-2011395-A1 Active compound combinations Bayer CropScience AG (DE) 2009-01-07 EP claimed
EP-2011397-A1 Active compound combinations Bayer CropScience AG (DE) 2009-01-07 EP claimed
WO-2008152092-A2 PESTICIDAL COMPOSITION COMPRISING A STRIGOLACTONE DERIVATIVE AND AN FUNGICIDE COMPOUND BAYER CROPSCIENCE SA (FR) 2008-12-18 WO claimed
WO-2008142029-A1 METHOD FOR IMPROVING THE BUD QUALITY OF A PLANT BAYER CROPSCIENCE SA (FR) 2008-11-27 WO claimed
WO-2008071672-A2 PESTICIDAL COMPOSITION COMPRISING A SYNTHETIC COMPOUND USEFUL AS NODULATION AGENT OF LEGUMINOUS PLANTS AND A FUNGICIDE COMPOUND BAYER CROPSCIENCE SA (FR) 2008-06-19 WO claimed