Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | POLB | P06746 | 4/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 8/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | LGMN | Q99538 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20522579 | 0.86 | LGMN (0.74) | ALDH1A1MEN1KMT2APOLBTDP1 | |
| SCHEMBL20522578 | 0.86 | ALDH1A1 (0.64) | ALDH1A1MEN1KMT2APOLBTDP1 | |
| SCHEMBL3436572 | 0.85 | ALDH1A1 (0.66) | ALDH1A1MEN1KMT2APOLBTDP1 | |
| SCHEMBL3436027 | 0.83 | LGMN (0.64) | ALDH1A1MEN1KMT2APOLBTDP1 | |
| SCHEMBL20522603 | 0.82 | MAPT (0.63) | ALDH1A1MEN1KMT2APOLBTDP1 | |
| SCHEMBL3139067 | 0.80 | MAPT (0.67) | ALDH1A1MEN1KMT2APOLBTDP1 | |
| SCHEMBL22712774 | 0.79 | KMT2A (0.51) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL13896504 | 0.79 | ALDH1A1 (0.69) | ALDH1A1MEN1KMT2APOLBTDP1 | |
| SCHEMBL22712744 | 0.79 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2APOLBTDP1 | |
| SCHEMBL20522647 | 0.76 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2APOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3601260-A1 | SUBSTITUTED CYCLYL-ACETIC ACID DERIVATIVES FOR THE TREATMENT OF METABOLIC DISORDERS | Takeda Pharmaceutical Company Limited (JP) | 2020-02-05 | — | — | EP | disclosed |
| CN-110678458-A | Substituted cyclyl-acetic acid derivatives for the treatment of metabolic disorders | 武田药品工业株式会社 | 2020-01-10 | — | — | CN | disclosed |
| WO-2018182050-A1 | SUBSTITUTED CYCLYL-ACETIC ACID DERIVATIVES FOR THE TREATMENT OF METABOLIC DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-10-04 | — | — | WO | disclosed |