SCHEMBL2052281

SCHEMBL2052281

O=[N+]([O-])CCC(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8279343 0.83 ALDH1A1 (0.46)
SCHEMBL18597638 0.78
SCHEMBL29412938 0.71 ALDH1A1 (0.32)
SCHEMBL3118936 0.71
SCHEMBL678569 0.71
SCHEMBL66347 0.69
SCHEMBL1603795 0.69
SCHEMBL400261 0.67
SCHEMBL16177524 0.67
SCHEMBL1678853 0.65 ALDH1A1 (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050044778-A1 Fuel compositions employing catalyst combustion structure OCTANE INTERNATIONAL, LTD. 2005-03-03 US claimed
EP-4612151-A1 PREPARATION OF IMIDAZOPYRIDINE AND IMIDAZOPYRIDAZINE DERIVATIVES AS NOVEL DIACYLGLYCERIDE O-ACYLTRANSFERASE 2 INHIBITORS Merck Sharp & Dohme LLC (US) 2025-09-10 EP disclosed
WO-2024097573-A1 PREPARATION OF IMIDAZOPYRIDINE AND IMIDAZOPYRIDAZINE DERIVATIVES AS NOVEL DIACYLGLYCERIDE O-ACYLTRANSFERASE 2 INHIBITORS MERCK SHARP & DOHME LLC (US) 2024-05-10 WO disclosed
EP-2571897-B1 NOVEL GLUCAGON LIKE PEPTIDE ANALOGS, COMPOSITION, AND METHOD OF USE BETTA PHARMACEUTICALS CO LTD (CN) 2014-11-05 EP disclosed
EP-2516434-A1 FUSED HETEROAROMATIC PYRROLIDINONES AS SYK INHIBITORS Takeda Pharmaceutical Company Limited (JP) 2012-10-31 EP disclosed
WO-2011079051-A1 FUSED HETEROAROMATIC PYRROLIDINONES AS SYK INHIBITORS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2011-06-30 WO disclosed
US-20050044778-A1 Fuel compositions employing catalyst combustion structure OCTANE INTERNATIONAL, LTD. 2005-03-03 US disclosed
US-5362477-A 19F magnetic resonance imaging agents which include a nitroxide moiety MALLINCKRODT MEDICAL, INC. (US) 1994-11-08 US disclosed
US-4459151-A Herbicidally active fluorine-containing 4,6-diamino-s-triazines BAYER AKTIENGESELLSCHAFT (DE) 1984-07-10 US disclosed
EP-0094538-A2 Fluor-containing 4,6-diamino-s-triazines, process and intermediates for their preparation, and their use as herbicides BAYER AG (DE) 1983-11-23 EP disclosed