Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 1.00 |
| ▸ | ABL1 | P00519 | 2/20 | 1.00 |
| ▸ | ABL2 | P42684 | 2/20 | 1.00 |
| ▸ | VCP | P55072 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.66 |
| ▸ | GALR2 | O43603 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | SYK | P43405 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.66 |
| ▸ | FBP1 | P09467 | 9/20 | 0.63 |
| ▸ | LCK | P06239 | 2/20 | 0.59 |
| ▸ | XDH | P47989 | 1/20 | 0.53 |
| ▸ | NQO2 | P16083 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2052283 | 1.00 | EGFR (1.00) | EGFRABL1ABL2VCPALDH1A1 | |
| SCHEMBL29371330 | 1.00 | EGFR (1.00) | EGFRABL1ABL2VCPALDH1A1 | |
| SCHEMBL3667077 | 0.96 | EGFR (0.93) | EGFRABL1ABL2VCPALDH1A1 | |
| SCHEMBL3667079 | 0.96 | EGFR (0.93) | EGFRABL1ABL2VCPALDH1A1 | |
| SCHEMBL13773077 | 0.84 | EGFR (0.72) | EGFRABL1ABL2VCPALDH1A1 | |
| SCHEMBL8010226 | 0.84 | EGFR (0.72) | EGFRABL1ABL2VCPALDH1A1 | |
| SCHEMBL11239202 | 0.84 | EGFR (0.72) | EGFRABL1ABL2VCPALDH1A1 | |
| SCHEMBL2027151 | 0.84 | EGFR (0.72) | EGFRABL1ABL2VCPALDH1A1 | |
| SCHEMBL2027152 | 0.84 | EGFR (0.72) | EGFRABL1ABL2VCPALDH1A1 | |
| SCHEMBL8012584 | 0.84 | EGFR (0.72) | EGFRABL1ABL2VCPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108794337-A | A kind of new preparation process of 3,4- dihydroxy-beta-nitrostyrene | 上海华堇生物技术有限责任公司 | 2018-11-13 | — | — | CN | claimed |
| JP-4425628-B2 | — | — | 2010-03-03 | — | — | JP | claimed |
| EP-1435894-A4 | CYTOPROTECTIVE COMPOUNDS, PHARMACEUTICAL AND COSMETIC FORMULATIONS, AND METHODS | GALILEO PHARMACEUTICALS INC (US) | 2005-07-06 | — | — | EP | claimed |
| JP-2005505519-A | — | — | 2005-02-24 | — | — | JP | claimed |
| EP-1435894-A2 | CYTOPROTECTIVE COMPOUNDS, PHARMACEUTICAL AND COSMETIC FORMULATIONS, AND METHODS | Galileo Pharmaceuticals, Inc. (US) | 2004-07-14 | — | — | EP | claimed |
| US-20030073712-A1 | Cytoprotective compounds, pharmaceutical and cosmetic formulations, and methods | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. | 2003-04-17 | — | — | US | claimed |
| WO-2003009807-A2 | CYTOPROTECTIVE COMPOUNDS, PHARMACEUTICAL AND COSMETIC FORMULATIONS, AND METHODS | GALILEO LABORATORIES, INC. (US) | 2003-02-06 | — | — | WO | claimed |
| US-20250326747-A1 | Benzoquinoline Inhibitors of Vesicular Monoamine Transporter 2 | AUSPEX PHARMACEUTICALS LLC | 2025-10-23 | — | — | US | disclosed |
| US-11505549-B2 | Process for preparation of Deutetrabenazine | ALAPARTHI, Lakshmi Prasad (IN) | 2022-11-22 | — | — | US | disclosed |
| US-20220267317-A1 | Benzoquinoline Inhibitors of Vesicular Monoamine Transporter 2 | AUSPEX PHARMACEUTICALS INC (US) | 2022-08-25 | — | — | US | disclosed |
| US-11421223-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. (US) | 2022-08-23 | — | — | US | disclosed |
| CN-112961093-A | Method for reducing C = C double bond of nitroolefin with high selectivity | 北京化工大学 | 2021-06-15 | — | — | CN | disclosed |
| US-20210047317-A1 | A NOVEL PROCESS FOR PREPARATION OF DEUTETRABENAZINE | ALAPARTHI, Lakshmi Prasad (IN) | 2021-02-18 | — | — | US | disclosed |
| US-20050113416-A1 | Cytoprotective compounds, pharmaceutical and cosmetic formulations, and methods | GALILEO PHARMACEUTICALS, INC. | 2005-05-26 | — | — | US | disclosed |
| EP-1435894-A2 | CYTOPROTECTIVE COMPOUNDS, PHARMACEUTICAL AND COSMETIC FORMULATIONS, AND METHODS | Galileo Pharmaceuticals, Inc. (US) | 2004-07-14 | — | — | EP | disclosed |
| US-20030073712-A1 | Cytoprotective compounds, pharmaceutical and cosmetic formulations, and methods | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. | 2003-04-17 | — | — | US | disclosed |
| WO-2003009807-A2 | CYTOPROTECTIVE COMPOUNDS, PHARMACEUTICAL AND COSMETIC FORMULATIONS, AND METHODS | GALILEO LABORATORIES, INC. (US) | 2003-02-06 | — | — | WO | disclosed |
| US-6162614-A | Sugar ester derivatives, reagents for measurement of hydrolase activity and methods for measurement of hydrolase activity | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 2000-12-19 | — | — | US | disclosed |
| EP-0346912-B1 | Sugar ester derivatives, reagents for measurement of hydrolase activity and methods for measurement of hydrolase activity | TOYO BOSEKI (JP) | 1997-12-17 | — | — | EP | disclosed |
| US-4153696-A | RENAL CIRCULATION PROMOTERS | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1979-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220267317-A1 | Benzoquinoline Inhibitors of Vesicular Monoamine Transporter 2 | SLC18A2, SLC6A2, SLC18A1 | EGFR 4787/4885ABL1 478/4885ABL2 1504/4885 |
| US-20030073712-A1 | Cytoprotective compounds, pharmaceutical and cosmetic formulations, and methods | HSF1, HMOX1, NQO1 | EGFR 3617/4885ABL1 4324/4885ABL2 4428/4885 |
| US-20250326747-A1 | Benzoquinoline Inhibitors of Vesicular Monoamine Transporter 2 | SLC18A2, SLC6A2, SLC18A1 | EGFR 4787/4885ABL1 478/4885ABL2 1504/4885 |
| US-11505549-B2 | Process for preparation of Deutetrabenazine | CYP4X1, DRD4, CHRM5 | EGFR 3309/4885ABL1 2741/4885ABL2 3222/4885 |
| US-20050113416-A1 | Cytoprotective compounds, pharmaceutical and cosmetic formulations, and methods | HSF1, HMOX1, NQO1 | EGFR 3617/4885ABL1 4324/4885ABL2 4428/4885 |
| US-20210047317-A1 | A NOVEL PROCESS FOR PREPARATION OF DEUTETRABENAZINE | DRD4, DDO, CYP4X1 | EGFR 3652/4885ABL1 3097/4885ABL2 3490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.