Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 2/20 | 0.31 |
| ▸ | CCR1 | P32246 | 2/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18258349 | 0.87 | ESR2 (0.59) | ESR2MAPK1MAPK14RAB9ALMNA | |
| SCHEMBL18244774 | 0.84 | ESR2 (0.50) | ESR2MAPK1MAPK14 | |
| SCHEMBL18244723 | 0.83 | ESR2 (0.42) | ESR2MAPK1MAPK14 | |
| SCHEMBL12919164 | 0.70 | CA1 (0.46) | TSHR | |
| SCHEMBL16743002 | 0.70 | ESR2 (0.59) | ESR2RAB9ALMNAKDM4E | |
| SCHEMBL2257887 | 0.70 | ESR2 (0.62) | ESR2CYP2C9 | |
| SCHEMBL17070013 | 0.69 | ELANE (0.54) | PPARA | |
| SCHEMBL863103 | 0.69 | MAOB (0.46) | NPC1RAB9ALMNACYP2C9PPARA | |
| SCHEMBL704145 | 0.69 | CA4 (0.37) | ESR2MAPK1TSHR | |
| SCHEMBL7096596 | 0.68 | ESR2 (0.46) | ESR2LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3601204-A1 | SUBSTITUTED (4'-HYDROXYPHENYL)CYCLOALKANE AND (4'-HYDROXYPHENYL)CYCLOALKENE COMPOUNDS AND USES THEREOF AS SELECTIVE AGONISTS OF THE ESTROGEN RECEPTOR BETA ISOFORM FOR ENHANCED MEMORY CONSOLIDATION | Marquette University (US) | 2020-02-05 | — | — | EP | disclosed |
| WO-2018183800-A1 | SUBSTITUTED (4'-HYDROXYPHENYL)CYCLOALKANE AND (4'-HYDROXYPHENYL)CYCLOALKENE COMPOUNDS AND USES THEREOF AS SELECTIVE AGONISTS OF THE ESTROGEN RECEPTOR BETA ISOFORM FOR ENHANCED MEMORY CONSOLIDATION | MARQUETTE UNIVERSITY (US) | 2018-10-04 | — | — | WO | disclosed |