Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 5/20 | 0.62 |
| ▸ | CDK5R1 | Q15078 | 5/20 | 0.62 |
| ▸ | GSK3B | P49841 | 5/20 | 0.62 |
| ▸ | CCNB2 | O95067 | 4/20 | 0.62 |
| ▸ | CDK1 | P06493 | 4/20 | 0.62 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.62 |
| ▸ | CCNB3 | Q8WWL7 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 9/20 | 0.48 |
| ▸ | HTR2C | P28335 | 7/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29908708 | 0.84 | MEN1 (0.61) | CDK5CDK5R1GSK3BCCNB2CDK1 | |
| SCHEMBL272876 | 0.84 | MEN1 (0.61) | CDK5CDK5R1GSK3BCCNB2CDK1 | |
| SCHEMBL4552964 | 0.84 | CDK1 (0.62) | CDK5CDK5R1GSK3BCCNB2CDK1 | |
| SCHEMBL20524909 | 0.82 | GSK3B (0.65) | CDK5CDK5R1GSK3BCCNB2CDK1 | |
| SCHEMBL6350624 | 0.77 | KDM4E (0.69) | CDK5GSK3BKDM4ELMNAGAA | |
| SCHEMBL5688188 | 0.76 | GSK3B (1.00) | CDK5CDK5R1GSK3BCCNB2CDK1 | |
| SCHEMBL20807162 | 0.71 | CCNB2 (0.53) | CDK5CDK5R1GSK3BCCNB2CDK1 | |
| SCHEMBL1985243 | 0.71 | MEN1 (0.71) | CDK5CDK5R1GSK3BCCNB2CDK1 | |
| SCHEMBL21724805 | 0.69 | PRKD1 (0.71) | CDK5GSK3BKDM4ELMNAGAA | |
| SCHEMBL2824450 | 0.68 | KDM4E (0.61) | CDK5CDK5R1GSK3BCCNB2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3600259-A1 | NOVEL PHARMACEUTICAL FORMULATIONS CONTAINING INDIRUBIN AND DERIVATIVES THEREOF AND METHODS OF MAKING AND USING THE SAME | Phosphorex, Inc. (US) | 2020-02-05 | — | — | EP | disclosed |
| WO-2018183631-A1 | NOVEL PHARMACEUTICAL FORMULATIONS CONTAINING INDIRUBIN AND DERIVATIVES THEREOF AND METHODS OF MAKING AND USING THE SAME | PHOSPHOREX, INC. (US) | 2018-10-04 | — | — | WO | disclosed |