Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.55 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.55 |
| ▸ | CDK1 | P06493 | 2/20 | 0.55 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.55 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.55 |
| ▸ | CDK2 | P24941 | 2/20 | 0.55 |
| ▸ | CDK9 | P50750 | 2/20 | 0.55 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.55 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.55 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.55 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.55 |
| ▸ | GSK3B | P49841 | 1/20 | 0.55 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL272876 | 1.00 | MEN1 (0.61) | MEN1KMT2AKDM4ECYP1A2HPGD | |
| SCHEMBL4552964 | 0.84 | CDK1 (0.62) | MEN1KMT2AKDM4ECYP1A2HTT | |
| SCHEMBL20524901 | 0.84 | CDK5 (0.62) | MEN1KMT2AKDM4ECYP1A2HPGD | |
| SCHEMBL20524909 | 0.82 | GSK3B (0.65) | MEN1KMT2AKDM4ECYP1A2HPGD | |
| SCHEMBL13837458 | 0.76 | MEN1 (0.65) | MEN1KMT2AKDM4ECYP1A2HPGD | |
| SCHEMBL797563 | 0.76 | KDM4E (1.00) | MEN1KMT2AKDM4ECYP1A2HPGD | |
| SCHEMBL20524896 | 0.74 | KDM4E (0.54) | MEN1KMT2AKDM4ECYP1A2HPGD | |
| SCHEMBL12126575 | 0.74 | CA1 (0.71) | MEN1KMT2AKDM4ECYP1A2HPGD | |
| SCHEMBL30063877 | 0.74 | CA1 (0.71) | MEN1KMT2AKDM4ECYP1A2HPGD | |
| SCHEMBL1394921 | 0.71 | CCNB2 (0.71) | MEN1KMT2AKDM4ECYP1A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11466252-B2 | Expansion and differentiation of inner ear supporting cells and methods of use thereof | MASSACHUSETTS EYE AND EAR INFIRMARY (US) | 2022-10-11 | — | — | US | disclosed |