Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 14/20 | 0.65 |
| ▸ | CDK5 | Q00535 | 13/20 | 0.65 |
| ▸ | CDK5R1 | Q15078 | 13/20 | 0.65 |
| ▸ | CCNB2 | O95067 | 13/20 | 0.65 |
| ▸ | CDK1 | P06493 | 13/20 | 0.65 |
| ▸ | CCNB1 | P14635 | 13/20 | 0.65 |
| ▸ | CCNB3 | Q8WWL7 | 13/20 | 0.65 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.65 |
| ▸ | CDK2 | P24941 | 3/20 | 0.65 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.65 |
| ▸ | GSK3A | P49840 | 4/20 | 0.52 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.50 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29908708 | 0.82 | MEN1 (0.61) | GSK3BCDK5CDK5R1CCNB2CDK1 | |
| SCHEMBL272876 | 0.82 | MEN1 (0.61) | GSK3BCDK5CDK5R1CCNB2CDK1 | |
| SCHEMBL20524901 | 0.82 | CDK5 (0.62) | GSK3BCDK5CDK5R1CCNB2CDK1 | |
| SCHEMBL4552964 | 0.82 | CDK1 (0.62) | GSK3BCDK5CDK5R1CCNB2CDK1 | |
| SCHEMBL15264418 | 0.80 | GSK3B (0.69) | GSK3BCDK5CDK5R1CCNB2CDK1 | |
| Paullone 2 SCHEMBL5688525 | 0.79 | GSK3B (1.00) | GSK3BCDK5CDK5R1CCNB2CDK1 | |
| Paullone 2 SCHEMBL30319785 | 0.79 | GSK3B (1.00) | GSK3BCDK5CDK5R1CCNB2CDK1 | |
| SCHEMBL2360505 | 0.70 | KDM4E (0.63) | GSK3BCDK5CDK5R1CCNB2CDK1 | |
| SCHEMBL6237963 | 0.69 | KDM4E (0.63) | GSK3BCDK5CDK2KDM4EMEN1 | |
| SCHEMBL1247669 | 0.69 | CHUK (0.63) | GSK3BCDK5CDK5R1CCNB2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3600259-A1 | NOVEL PHARMACEUTICAL FORMULATIONS CONTAINING INDIRUBIN AND DERIVATIVES THEREOF AND METHODS OF MAKING AND USING THE SAME | Phosphorex, Inc. (US) | 2020-02-05 | — | — | EP | disclosed |
| WO-2018183631-A1 | NOVEL PHARMACEUTICAL FORMULATIONS CONTAINING INDIRUBIN AND DERIVATIVES THEREOF AND METHODS OF MAKING AND USING THE SAME | PHOSPHOREX, INC. (US) | 2018-10-04 | — | — | WO | disclosed |