Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 4/20 | 0.35 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20525358 | 0.92 | EGLN1 (0.42) | EGLN1CCR5SYKCNR1CNR2 | |
| SCHEMBL20525414 | 0.91 | PARP1 (0.42) | EGLN1CCR5 | |
| SCHEMBL20525400 | 0.89 | PARP1 (0.41) | EGLN1CCR5CNR1CNR2 | |
| SCHEMBL20525454 | 0.89 | SYK (0.42) | EGLN1SYKFGFR1FGFR4 | |
| SCHEMBL20525469 | 0.88 | PIK3CA (0.42) | EGLN1 | |
| SCHEMBL20525424 | 0.88 | EGLN1 (0.38) | EGLN1CCR5GLO1SYKTLR9 | |
| SCHEMBL20525438 | 0.88 | DRD2 (0.42) | EGLN1CCR5SYK | |
| SCHEMBL20525339 | 0.87 | PARP1 (0.41) | EGLN1GLO1 | |
| SCHEMBL20525460 | 0.87 | PARP1 (0.41) | EGLN1GLO1SYK | |
| SCHEMBL20525322 | 0.86 | EGLN1 (0.35) | EGLN1CCR5GLO1SYKTLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3080125-B1 | NOVEL AZAINDOLE DERIVATIVES AS SELECTIVE HISTONE DEACETYLASE (HDAC) INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2018-10-10 | — | — | EP | disclosed |