Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 4/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20525317 | 0.92 | EGLN1 (0.39) | EGLN1CCR5SYKCNR1CNR2 | |
| SCHEMBL20525414 | 0.92 | PARP1 (0.42) | EGLN1PARP1CCR5SCN9ASIGMAR1 | |
| SCHEMBL20525400 | 0.92 | PARP1 (0.41) | EGLN1PARP1CCR5CNR1CNR2 | |
| SCHEMBL20525454 | 0.92 | SYK (0.42) | EGLN1PARP1SYK | |
| SCHEMBL20525469 | 0.91 | PIK3CA (0.42) | EGLN1PARP1 | |
| SCHEMBL20525424 | 0.91 | EGLN1 (0.38) | EGLN1CCR5SYKCNR1CNR2 | |
| SCHEMBL20525438 | 0.90 | DRD2 (0.42) | EGLN1CCR5SYK | |
| SCHEMBL20525339 | 0.88 | PARP1 (0.41) | EGLN1PARP1 | |
| SCHEMBL20525460 | 0.88 | PARP1 (0.41) | EGLN1PARP1SYK | |
| SCHEMBL20525322 | 0.86 | EGLN1 (0.35) | EGLN1CCR5SYKCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3080125-B1 | NOVEL AZAINDOLE DERIVATIVES AS SELECTIVE HISTONE DEACETYLASE (HDAC) INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2018-10-10 | — | — | EP | disclosed |