Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.67 |
| ▸ | CA4 | P22748 | 4/20 | 0.67 |
| ▸ | CA6 | P23280 | 4/20 | 0.67 |
| ▸ | CA5A | P35218 | 4/20 | 0.67 |
| ▸ | CA7 | P43166 | 4/20 | 0.67 |
| ▸ | CA9 | Q16790 | 4/20 | 0.67 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.67 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.67 |
| ▸ | MET | P08581 | 9/20 | 0.56 |
| ▸ | TTR | P02766 | 3/20 | 0.55 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.50 |
| ▸ | SNCA | P37840 | 1/20 | 0.50 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzyl Ferulate SCHEMBL15419733 | 0.82 | CA12 (1.00) | CA12CA4CA6CA5ACA7 | |
| Benzyl Ferulate SCHEMBL16155887 | 0.82 | CA12 (1.00) | CA12CA4CA6CA5ACA7 | |
| SCHEMBL16150378 | 0.75 | CA1 (0.42) | CA12CA4CA6CA5ACA7 | |
| SCHEMBL28869313 | 0.73 | CA12 (0.82) | CA12CA4CA6CA5ACA7 | |
| SCHEMBL16155888 | 0.73 | CA12 (0.82) | CA12CA4CA6CA5ACA7 | |
| SCHEMBL7048864 | 0.73 | MET (0.83) | CA12CA4CA6CA5ACA7 | |
| SCHEMBL7048865 | 0.73 | MET (0.83) | CA12CA4CA6CA5ACA7 | |
| SCHEMBL15384085 | 0.73 | CA12 (0.81) | CA12CA4CA6CA5ACA7 | |
| SCHEMBL29009258 | 0.73 | MET (0.86) | CA12CA4CA6CA5ACA7 | |
| SCHEMBL2792633 | 0.72 | TTR (1.00) | CA12CA4CA6CA5ACA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2981254-B1 | THERAPEUTIC COMPOSITIONS COMPRISING EXTRACTS OF PROPOLIS AND USES THEREOF FOR THE TREATMENT OF GASTRIC CANCER | MANUKA HEALTH NEW ZEALAND LTD (NZ) | 2018-10-10 | — | — | EP | disclosed |