Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.82 |
| ▸ | CA4 | P22748 | 3/20 | 0.82 |
| ▸ | CA6 | P23280 | 3/20 | 0.82 |
| ▸ | CA5A | P35218 | 3/20 | 0.82 |
| ▸ | CA7 | P43166 | 3/20 | 0.82 |
| ▸ | CA9 | Q16790 | 3/20 | 0.82 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.82 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.82 |
| ▸ | TTR | P02766 | 5/20 | 0.78 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.74 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.74 |
| ▸ | MET | P08581 | 3/20 | 0.63 |
| ▸ | MAOA | P21397 | 1/20 | 0.63 |
| ▸ | MAOB | P27338 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.60 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16155888 | 1.00 | CA12 (0.82) | CA12CA4CA6CA5ACA7 | |
| Benzyl Ferulate SCHEMBL16155887 | 0.90 | CA12 (1.00) | CA12CA4CA6CA5ACA7 | |
| Benzyl Ferulate SCHEMBL15419733 | 0.90 | CA12 (1.00) | CA12CA4CA6CA5ACA7 | |
| SCHEMBL15384085 | 0.90 | CA12 (0.81) | CA12CA4CA6CA5ACA7 | |
| SCHEMBL20914958 | 0.88 | TTR (1.00) | CA12CA4CA6CA5ACA7 | |
| SCHEMBL9550145 | 0.86 | CA12 (0.76) | CA12CA4CA6CA5ACA7 | |
| SCHEMBL20914973 | 0.86 | TTR (0.87) | CA12CA4CA6CA5ACA7 | |
| Benzyl Caffeate SCHEMBL1877243 | 0.85 | AKR1B10 (1.00) | CA12CA4CA6CA5ACA7 | |
| Benzyl Caffeate SCHEMBL1659796 | 0.85 | AKR1B10 (1.00) | CA12CA4CA6CA5ACA7 | |
| SCHEMBL7048864 | 0.85 | MET (0.83) | CA12CA4CA6CA5ACA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109310660-B | Therapeutic compositions and uses thereof | 蜜纽康新西兰有限公司 | 2023-07-11 | — | — | CN | disclosed |
| CN-109310660-A | Therapeutic combination and application thereof | 蜜纽康新西兰有限公司 | 2019-02-05 | — | — | CN | disclosed |