SCHEMBL20526421

SCHEMBL20526421

[Pt]C1C=Cc2ccccc2O1

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
KMT2A Q03164 1/20 0.33
P2RY6 Q15077 1/20 0.31
HTR2C P28335 1/20 0.30
HTR2B P41595 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30407118 0.77 KDM4E (0.35) KDM4EMEN1ALDH1A1MAPTKMT2A
SCHEMBL30485934 0.76 KDM4E (0.37) KDM4EMEN1ALDH1A1MAPTKMT2A
SCHEMBL15761031 0.76 KDM4E (0.37) KDM4EMEN1ALDH1A1MAPTKMT2A
SCHEMBL293045 0.76 KDM4E (0.37) KDM4EMEN1ALDH1A1MAPTKMT2A
SCHEMBL30096256 0.76 KDM4E (0.38) KDM4EMEN1ALDH1A1MAPTKMT2A
SCHEMBL2006247 0.74 KDM4E (0.33) KDM4EMEN1ALDH1A1MAPTKMT2A
SCHEMBL293044 0.74 KDM4E (0.33) KDM4EMEN1ALDH1A1MAPTKMT2A
SCHEMBL3069884 0.74 KDM4E (0.37) KDM4EMEN1ALDH1A1MAPTKMT2A
SCHEMBL276958 0.74 P2RY6 (0.34) KDM4EMEN1ALDH1A1MAPTKMT2A
SCHEMBL1077043 0.74 P2RY6 (0.34) KDM4EMEN1ALDH1A1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3383954-A1 PHOTOACTIVATABLE MULTI-COMPONENT SYSTEMS FOR PRODUCING A FOAMED SILICONE COMPOSITION Sonderhoff Chemicals GmbH (DE) 2018-10-10 EP disclosed
CN-102933366-A Integrated irradiation device MOMENTIVE PERFORMANCE MAT INC 2013-02-13 CN disclosed
CN-102015845-A Process for the continuous manufacturing of shaped articles and use of silicone rubber compositions in that process MOMENTIVE PERFORMANCE MAT INC 2011-04-13 CN disclosed