Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30821601 | 1.00 | KDM4E (0.37) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| Cyanide SCHEMBL28541939 | 0.94 | KDM4E (0.34) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL30096256 | 0.80 | KDM4E (0.38) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL30407118 | 0.77 | KDM4E (0.35) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL15761031 | 0.76 | KDM4E (0.37) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL293045 | 0.76 | KDM4E (0.37) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL30485934 | 0.76 | KDM4E (0.37) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL2006247 | 0.74 | KDM4E (0.33) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL1077043 | 0.74 | P2RY6 (0.34) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL276958 | 0.74 | P2RY6 (0.34) | KDM4EMEN1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 184 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118164945-A | Chiral 2-amino benzopyran derivative, preparation method and application thereof | 华东理工大学 | 2024-06-11 | — | — | CN | claimed |
| CN-117843669-A | Amino benzopyran cyanine compound and application thereof | 浙江大学长三角智慧绿洲创新中心 | 2024-04-09 | — | — | CN | claimed |
| CN-112939919-B | 2-aminobenzopyran compound and application thereof in pesticide | 西华大学 | 2023-02-03 | — | — | CN | claimed |
| CN-112939919-A | 2-aminobenzopyran compound and application thereof in pesticide | 西华大学 | 2021-06-11 | — | — | CN | claimed |
| CN-103483306-B | Method for preparing 2-amino-2-chromene derivatives by using polyamino ionic liquid as catalyst | UNIV ANHUI TECHNOLOGY | 2014-12-10 | — | — | CN | claimed |
| CN-103483306-A | Method for preparing 2-amino-2-chromene derivatives by using polyamino ionic liquid as catalyst | UNIV ANHUI TECHNOLOGY | 2014-01-01 | — | — | CN | claimed |
| EP-1535918-B1 | PROCESS FOR PRODUCING AMINOBENZOPYRAN COMPOUND | NISSAN CHEMICAL IND LTD (JP) | 2010-11-03 | — | — | EP | claimed |
| US-7683189-B2 | Process for producing aminobenzopyran compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-03-23 | — | — | US | claimed |
| WO-2010002075-A1 | METHODS FOR PREPARING AMIDE DERIVATIVES | PHARMACOSTECH CO., LTD. (KR) | 2010-01-07 | — | — | WO | claimed |
| CN-100363358-C | Process for producing aminobenzopyran compound | NISSAN CHEMICAL IND LTD (JP) | 2008-01-23 | — | — | CN | claimed |
| US-20050192444-A1 | Process for producing aminobenzopyran compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2005-09-01 | — | — | US | claimed |
| EP-1535918-A1 | PROCESS FOR PRODUCING AMINOBENZOPYRAN COMPOUND | Nissan Chemical Industries, Ltd. (JP) | 2005-06-01 | — | — | EP | claimed |
| EP-1392283-A4 | SUBSTITUTED COUMARINS AND QUINOLINES AS CASPASE ACTIVATORS | CYTOVIA INC (US) | 2004-10-20 | — | — | EP | claimed |
| CN-1147491-C | Acridine carboxylic ester compound, preparation and medicinal composition thereof | ɪά��ʵ���� | 2004-04-28 | — | — | CN | claimed |
| EP-1392283-A1 | SUBSTITUTED COUMARINS AND QUINOLINES AS CASPASES ACTIVATORS | Cytovia, Inc. (US) | 2004-03-03 | — | — | EP | claimed |
| US-20030114485-A1 | Substituted coumarins and quinolines and analogs as activators of caspases and inducers of apoptosis and the use thereof | CYTOVIA, INC. | 2003-06-19 | — | — | US | claimed |
| WO-2002092076-A1 | SUBSTITUTED COUMARINS AND QUINOLINES AS CASPASES ACTIVATORS | CYTOVIA, INC. (US) | 2002-11-21 | — | — | WO | claimed |
| CN-1279239-A | Acridine carboxylic ester compound, preparation and medicinal composition thereof | ADIR (FR) | 2001-01-10 | — | — | CN | claimed |
| EP-0623608-A1 | BENZOPYRAN DERIVATIVE, PRODUCTION THEREOF, AND PHARMACEUTICAL PREPARATION CONTAINING THE SAME AS ACTIVE INGREDIENT | TEIJIN LIMITED (JP) | 1994-11-09 | — | — | EP | claimed |
| EP-0300908-B1 | BENZOPYRAN DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | RHONE-POULENC SANTE (FR) | 1992-03-18 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050192444-A1 | Process for producing aminobenzopyran compound | ALDH7A1, ACMSD, MANBA | KDM4E 452/4885MEN1 3030/4885ALDH1A1 195/4885 |
| US-20030114485-A1 | Substituted coumarins and quinolines and analogs as activators of caspases and inducers of apoptosis and the use thereof | CASP7, CASP1, CASP5 | KDM4E 2846/4885MEN1 2460/4885ALDH1A1 1275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.