Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30485934 | 1.00 | KDM4E (0.37) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL15761031 | 1.00 | KDM4E (0.37) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL28363725 | 0.86 | KDM4E (0.31) | KDM4EALDH1A1HPGD | |
| SCHEMBL12491545 | 0.79 | KDM4E (0.31) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL30407118 | 0.79 | KDM4E (0.35) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL30096256 | 0.77 | KDM4E (0.38) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL3069884 | 0.76 | KDM4E (0.37) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3209487 | 0.76 | KDM4E (0.33) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL1077043 | 0.76 | P2RY6 (0.34) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL20526421 | 0.76 | KDM4E (0.33) | KDM4EALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113330004-A | Differential solubility driven asymmetric transformation process for substituted 2H-chromene-3-carboxylic acids | 株式会社AskAt | 2021-08-31 | — | — | CN | claimed |
| EP-0184257-B1 | BENZOXAZOL- AND BENZOTHIAZOLAMINE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-07-25 | — | — | EP | claimed |
| US-4861785-A | Benzoxazol-and benzothiazolamine derivatives, useful as anti-anoxic agents | JANSSEN PHARMACEUTICA N.V. (BE) | 1989-08-29 | — | — | US | claimed |
| EP-0184257-A1 | Benzoxazol- and benzothiazolamine derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1986-06-11 | — | — | EP | claimed |
| EP-0027835-A1 | Process for producing cis-(+,-)-3,4-dihydro-N,N,2-trimethyl-2H-1-benzopyran-3-amine, intermediates produced thereby and their preparation | WARNER-LAMBERT COMPANY (US) | 1981-05-06 | — | — | EP | claimed |
| US-4203895-A | Process for the preparation of cis-(±)-3,4-dihydro-N,N,2-trimethyl-2H-1-benzopyran-3-amine and intermediates produced thereby | WARNER-LAMBERT COMPANY (US) | 1980-05-20 | — | — | US | claimed |
| US-12577526-B2 | Massively parallel on-chip construction of synthetic microbial communities | THE BROAD INSTITUTE, INC. (US) | 2026-03-17 | — | — | US | disclosed |
| US-20250376656-A1 | MASSIVELY PARALLEL ON-CHIP CONSTRUCTION OF SYNTHETIC MICROBIAL COMMUNITIES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2025-12-11 | — | — | US | disclosed |
| US-20250154122-A1 | PROCESS FOR THE PREPARATION OF COMPOUNDS COMPRISING A 2,5-DIHYDROBENZOXEPINE STRUCTURE BY PHOTOCHEMICAL REARRANGEMENT | ECOLE POLYTECHNIQUE (FR) | 2025-05-15 | — | — | US | disclosed |
| CN-118984826-A | Method for preparing compounds comprising 2, 5-dihydrobenzoxazepine structures by photochemical rearrangement | 巴黎综合理工学院 | 2024-11-19 | — | — | CN | disclosed |
| WO-2023156461-A1 | PROCESS FOR THE PREPARATION OF COMPOUNDS COMPRISING A 2,5-DIHYDROBENZOXEPINE STRUCTURE BY PHOTOCHEMICAL REARRANGEMENT | ECOLE POLYTECHNIQUE (FR) | 2023-08-24 | — | — | WO | disclosed |
| US-20220228190-A1 | MASSIVELY PARALLEL ON-CHIP CONSTRUCTION OF SYNTHETIC MICROBIAL COMMUNITIES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2022-07-21 | — | — | US | disclosed |
| WO-2022040600-A1 | COMPOUNDS AS GLP-1R AGONISTS | TERNS PHARMACEUTICALS, INC. (US) | 2022-02-24 | — | — | WO | disclosed |
| US-5941704-A | Crown cage for ball bearing and dental hand piece including the same | KOYO SEIKO CO., LTD. (JP) | 1999-08-24 | — | — | US | disclosed |
| US-5010198-A | Intermediates for the synthesis of benzoxazol- and benzothiazolamine derivatives, useful as anti-anoxic agents | JANSSEN PHARMACEUTICA N.V. (BE) | 1991-04-23 | — | — | US | disclosed |
| EP-0184257-B1 | BENZOXAZOL- AND BENZOTHIAZOLAMINE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-07-25 | — | — | EP | disclosed |
| US-4861785-A | Benzoxazol-and benzothiazolamine derivatives, useful as anti-anoxic agents | JANSSEN PHARMACEUTICA N.V. (BE) | 1989-08-29 | — | — | US | disclosed |
| EP-0184257-A1 | Benzoxazol- and benzothiazolamine derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1986-06-11 | — | — | EP | disclosed |
| EP-0027835-A1 | Process for producing cis-(+,-)-3,4-dihydro-N,N,2-trimethyl-2H-1-benzopyran-3-amine, intermediates produced thereby and their preparation | WARNER-LAMBERT COMPANY (US) | 1981-05-06 | — | — | EP | disclosed |
| US-4203895-A | Process for the preparation of cis-(±)-3,4-dihydro-N,N,2-trimethyl-2H-1-benzopyran-3-amine and intermediates produced thereby | WARNER-LAMBERT COMPANY (US) | 1980-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250154122-A1 | PROCESS FOR THE PREPARATION OF COMPOUNDS COMPRISING A 2,5-DIHYDROBENZOXEPINE STRUCTURE BY PHOTOCHEMICAL REARRANGEMENT | DHPS, DDT, DHX15 | KDM4E 259/4885ALDH1A1 1913/4885HPGD 396/4885 |
| US-12577526-B2 | Massively parallel on-chip construction of synthetic microbial communities | STUB1, SAMM50, CD14 | KDM4E 2737/4885ALDH1A1 1629/4885HPGD 4563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.