Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL20527475

CCC(=O)O.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 2/20 0.62
CYP2D6 P10635 1/20 0.39
TSHR P16473 1/20 0.39
CYP2C19 P33261 1/20 0.39
HIF1A Q16665 1/20 0.39
FAAH O00519 8/20 0.39
ACLY P53396 2/20 0.39
HDAC3 O15379 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
CES1 P23141 5/20 0.37
CES2 O00748 2/20 0.37
MEN1 O00255 2/20 0.37
CYP1A2 P05177 2/20 0.37
KMT2A Q03164 2/20 0.37
HSD17B10 Q99714 1/20 0.37
TDP1 Q9NUW8 2/20 0.37
ALDH1A1 P00352 2/20 0.37
THRB P10828 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL4485807 1.00 FFAR3 (0.62) FFAR3CYP2D6TSHRCYP2C19HIF1A
Succinic Acid SCHEMBL27603519 0.87 FFAR3 (0.48) FFAR3TSHRFAAHHDAC3HDAC1
Trifluoroacetic Acid SCHEMBL9785203 0.87 FFAR3 (0.62) FFAR3TSHRFAAHHDAC3HDAC1
Trifluoroacetic Acid SCHEMBL31031817 0.87 FAAH (0.42) FFAR3CYP2D6TSHRCYP2C19HIF1A
Trifluoroacetic Acid SCHEMBL27841664 0.87 FAAH (0.42) FFAR3CYP2D6TSHRCYP2C19HIF1A
Trifluoroacetic Acid SCHEMBL29603858 0.85 ALDH1A1 (0.59) FFAR3FAAHCES1CES2MEN1
Trifluoroacetic Acid SCHEMBL27943966 0.85 FFAR3 (0.42) FFAR3TSHRFAAHCES1CES2
Trifluoroacetic Acid SCHEMBL27632684 0.85 TDP1 (0.59) FFAR3TSHRFAAHCES1CES2
Trifluoroacetic Acid SCHEMBL3794549 0.84 FAAH (0.40) FFAR3CYP2D6TSHRCYP2C19HIF1A
Trifluoroacetic Acid SCHEMBL30324569 0.84 FAAH (0.40) FFAR3CYP2D6TSHRCYP2C19HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115052862-A MASP-2 inhibitors and methods of use 奥默罗斯公司 2022-09-13 CN disclosed
US-20180290976-A1 LSD1 INHIBITORS AND USES THEREOF CONSTELLATION PHARMACEUTICALS, INC. 2018-10-11 US disclosed
CN-1541115-A Smulaneous imaging of cardiac perfusion and vitronection receptor targeted imaging agent ����˹�ж�-����˹˹����ҩƷ��˾ 2004-10-27 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180290976-A1 LSD1 INHIBITORS AND USES THEREOF KDM1B, KDM1A, KDM2A FFAR3 2145/4885CYP2D6 1305/4885TSHR 4232/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.