SCHEMBL20527617

SCHEMBL20527617

C[n+]1ccn(CC(=O)c2ccccc2F)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
KMT2A Q03164 3/20 0.46
PTPN1 P18031 1/20 0.42
ERCC5 P28715 1/20 0.42
FEN1 P39748 1/20 0.42
MEN1 O00255 2/20 0.42
RECQL P46063 1/20 0.42
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
CTNNB1 P35222 2/20 0.40
WNT3A P56704 2/20 0.40
CES2 O00748 1/20 0.40
CES1 P23141 1/20 0.40
GAA P10253 1/20 0.38
ALDH1A1 P00352 1/20 0.38
ALOX15 P16050 1/20 0.38
THRB P10828 1/20 0.37
HPGD P15428 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20527659 0.84 LMNA (0.55) LMNASMN1; SMN2KMT2AERCC5FEN1
Bromide SCHEMBL3854789 0.81 LMNA (0.52) LMNASMN1; SMN2KMT2AMEN1RECQL
SCHEMBL20527501 0.81 LMNA (0.51) LMNASMN1; SMN2KMT2APTPN1MEN1
SCHEMBL20527503 0.81 LMNA (0.51) LMNASMN1; SMN2KMT2AMEN1RECQL
Bromide SCHEMBL3850911 0.75 SMN1; SMN2 (0.74) LMNASMN1; SMN2KMT2APTPN1MEN1
Hydrochloric Acid SCHEMBL3847700 0.73 SMN1; SMN2 (0.52) LMNASMN1; SMN2KMT2AERCC5FEN1
SCHEMBL10531134 0.72 SMN1; SMN2 (0.74) LMNASMN1; SMN2KMT2AMEN1RECQL
Phthalic Acid SCHEMBL21808394 0.72 ALDH1A1 (0.44) LMNASMN1; SMN2KMT2AMEN1NPC1
SCHEMBL20527499 0.71 LMNA (0.53) LMNASMN1; SMN2KMT2AERCC5FEN1
Bromide SCHEMBL3849689 0.71 SMN1; SMN2 (0.64) LMNASMN1; SMN2KMT2APTPN1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200207940-A1 Carbon Fiber Recovery Compositions and Methods THE BOEING COMPANY 2020-07-02 US claimed
US-10611892-B2 Carbon fiber recovery compositions and methods THE BOEING COMPANY (US) 2020-04-07 US claimed
US-20180291174-A1 Carbon Fiber Recovery Compositions and Methods THE BOEING COMPANY 2018-10-11 US claimed
US-11377535-B2 Carbon fiber recovery compositions and methods THE BOEING COMPANY (US) 2022-07-05 US disclosed
US-20200207940-A1 Carbon Fiber Recovery Compositions and Methods THE BOEING COMPANY 2020-07-02 US disclosed
US-10611892-B2 Carbon fiber recovery compositions and methods THE BOEING COMPANY (US) 2020-04-07 US disclosed
US-20180291174-A1 Carbon Fiber Recovery Compositions and Methods THE BOEING COMPANY 2018-10-11 US disclosed