SCHEMBL20528646

SCHEMBL20528646

c1ccc(CNC2COC2)cc1

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GRIN2B Q13224 4/20 0.56
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
RAB9A P51151 1/20 0.52
ACHE P22303 4/20 0.51
BACE1 P56817 4/20 0.51
BCHE P06276 3/20 0.51
FYN P06241 1/20 0.51
KDM1A O60341 1/20 0.47
MAOA P21397 1/20 0.47
OPRM1 P35372 2/20 0.46
OPRL1 P41146 2/20 0.46
CARM1 Q86X55 1/20 0.45
PRMT6 Q96LA8 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32675244 0.85 GRIN2B (0.54) GRIN2BMEN1KMT2ARAB9AACHE
SCHEMBL3937405 0.85 GRIN2B (0.54) GRIN2BMEN1KMT2ARAB9AACHE
SCHEMBL23948575 0.85 GRIN2B (0.50) GRIN2BMEN1KMT2ARAB9AACHE
SCHEMBL18290472 0.82 LTA4H (0.62) GRIN2BMEN1KMT2ARAB9AACHE
SCHEMBL30164338 0.82 LTA4H (0.62) GRIN2BMEN1KMT2ARAB9AACHE
SCHEMBL18792185 0.82 LTA4H (0.62) GRIN2BMEN1KMT2ARAB9AACHE
SCHEMBL19583124 0.82 LTA4H (0.50) GRIN2BMEN1KMT2ARAB9AACHE
SCHEMBL17714473 0.82 LTA4H (0.50) GRIN2BMEN1KMT2ARAB9AACHE
SCHEMBL19583125 0.82 LTA4H (0.50) GRIN2BMEN1KMT2ARAB9AACHE
SCHEMBL663239 0.80 GRIN2B (0.74) GRIN2BMEN1KMT2ARAB9AACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117700373-B Morpholine ring compound and derivative, preparation method and application 华中师范大学 2026-02-06 CN disclosed
CN-117700373-A Morpholine ring compound and derivative, preparation method and application 华中师范大学 2024-03-15 CN disclosed
CN-117700373-A Morpholine ring compound and derivative, preparation method and application 华中师范大学 2024-03-15 CN disclosed
CN-108689951-B Triazole compound and application thereof in agriculture 东莞市东阳光农药研发有限公司 2020-05-19 CN disclosed
EP-3606910-A1 TRIAZOLE COMPOUND AND USE THEREOF IN AGRICULTURE Dongguan Hec Pesticides R&D Co., Ltd. (CN) 2020-02-12 EP disclosed
WO-2018184579-A1 TRIAZOLE COMPOUND AND USE THEREOF IN AGRICULTURE DONGGUAN HEC TECH R&D CO., LTD. (CN) 2018-10-11 WO disclosed