Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 15/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20528686 | 0.78 | HDAC1 (0.47) | HDAC6HDAC1HDAC5HDAC8 | |
| SCHEMBL21899954 | 0.76 | HDAC4 (0.69) | HDAC6HDAC1HDAC5HDAC8HDAC4 | |
| SCHEMBL20528700 | 0.74 | HDAC1 (0.47) | HDAC6HDAC1HDAC5HDAC8 | |
| SCHEMBL22076049 | 0.74 | HDAC4 (0.48) | HDAC6HDAC1HDAC5HDAC8HDAC4 | |
| SCHEMBL20448880 | 0.73 | HDAC1 (0.58) | HDAC6HDAC1HDAC5HDAC8 | |
| SCHEMBL29975221 | 0.70 | HDAC1 (0.43) | HDAC6HDAC1HDAC5HDAC8 | |
| SCHEMBL20528682 | 0.70 | HDAC1 (0.51) | HDAC6HDAC1HDAC5HDAC8 | |
| SCHEMBL20528694 | 0.69 | HDAC6 (0.45) | HDAC6HDAC1HDAC5HDAC8HDAC4 | |
| SCHEMBL21380538 | 0.68 | HDAC6 (0.55) | HDAC6HDAC1HDAC5HDAC8HDAC4 | |
| SCHEMBL23161638 | 0.67 | HDAC1 (0.53) | HDAC6HDAC1HDAC5HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018184988-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-10-11 | — | — | WO | disclosed |