Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 20/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 20/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 18/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 13/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29966357 | 0.88 | HDAC1 (0.41) | HDAC1HDAC6HDAC5HDAC8 | |
| SCHEMBL29362560 | 0.80 | HDAC1 (0.59) | HDAC1HDAC6HDAC5HDAC8 | |
| SCHEMBL19476116 | 0.80 | HDAC1 (0.59) | HDAC1HDAC6HDAC5HDAC8 | |
| SCHEMBL20528677 | 0.78 | HDAC1 (0.44) | HDAC1HDAC6HDAC5HDAC8 | |
| SCHEMBL20528700 | 0.78 | HDAC1 (0.47) | HDAC1HDAC6HDAC5HDAC8 | |
| SCHEMBL20528686 | 0.77 | HDAC1 (0.47) | HDAC1HDAC6HDAC5HDAC8 | |
| SCHEMBL20528695 | 0.77 | HDAC4 (0.57) | HDAC1HDAC6HDAC5HDAC8 | |
| SCHEMBL20528673 | 0.76 | HDAC6 (0.45) | HDAC1HDAC6HDAC5HDAC8 | |
| SCHEMBL29363267 | 0.75 | HDAC6 (0.48) | HDAC1HDAC6HDAC5HDAC8 | |
| SCHEMBL18795842 | 0.75 | HDAC6 (0.48) | HDAC1HDAC6HDAC5HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018184988-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-10-11 | — | — | WO | disclosed |