Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 20/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 20/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 20/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20528700 | 0.82 | HDAC1 (0.47) | HDAC1HDAC6HDAC5HDAC8 | |
| SCHEMBL20528678 | 0.78 | HDAC6 (0.46) | HDAC1HDAC6HDAC5HDAC8 | |
| SCHEMBL20528682 | 0.77 | HDAC1 (0.51) | HDAC1HDAC6HDAC5HDAC8 | |
| SCHEMBL21543834 | 0.73 | HDAC6 (0.57) | HDAC1HDAC6HDAC5HDAC8 | |
| SCHEMBL29966955 | 0.72 | HDAC6 (0.39) | HDAC1HDAC6HDAC5HDAC8 | |
| SCHEMBL29922625 | 0.72 | HDAC6 (0.46) | HDAC1HDAC6HDAC5HDAC8 | |
| SCHEMBL20528677 | 0.71 | HDAC1 (0.44) | HDAC1HDAC6HDAC5HDAC8 | |
| Hydrochloric Acid SCHEMBL29975002 | 0.71 | HDAC6 (0.45) | HDAC1HDAC6HDAC5HDAC8 | |
| SCHEMBL19476116 | 0.71 | HDAC1 (0.59) | HDAC1HDAC6HDAC5HDAC8 | |
| SCHEMBL29362560 | 0.71 | HDAC1 (0.59) | HDAC1HDAC6HDAC5HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018185211-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-10-11 | — | — | WO | disclosed |
| WO-2018184988-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-10-11 | — | — | WO | disclosed |