SCHEMBL19476116

SCHEMBL19476116

Cc1ccc(-c2noc(C(F)(F)F)n2)c(F)c1

nearest known ligand 0.59

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 20/20 0.59
HDAC6 Q9UBN7 20/20 0.59
HDAC5 Q9UQL6 20/20 0.59
HDAC8 Q9BY41 11/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29362560 1.00 HDAC1 (0.59) HDAC1HDAC6HDAC5HDAC8
SCHEMBL19042598 0.82 HDAC1 (0.58) HDAC1HDAC6HDAC5HDAC8
SCHEMBL28509756 0.82 HDAC6 (0.55) HDAC1HDAC6HDAC5HDAC8
SCHEMBL20528673 0.81 HDAC6 (0.45) HDAC1HDAC6HDAC5HDAC8
SCHEMBL12112396 0.81 L3MBTL1 (0.47) HDAC1HDAC6HDAC5HDAC8
SCHEMBL20528682 0.80 HDAC1 (0.51) HDAC1HDAC6HDAC5HDAC8
SCHEMBL19464122 0.78 HDAC1 (0.54) HDAC1HDAC6HDAC5HDAC8
SCHEMBL18205191 0.78 HDAC6 (0.55) HDAC1HDAC6HDAC5HDAC8
SCHEMBL19463029 0.78 HDAC1 (0.65) HDAC1HDAC6HDAC5HDAC8
SCHEMBL29712282 0.78 HDAC6 (0.55) HDAC1HDAC6HDAC5HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250338848-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2025-11-06 US disclosed
US-20240284908-A1 Fungicidal Compositions SYNGENTA PARTICIPATIONS AG (CH) 2024-08-29 US disclosed
US-11974572-B2 Fungicidal compositions SYGENTA PARTICIPATIONS AG (CH) 2024-05-07 US disclosed
EP-3644743-B1 FUNGICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2022-10-26 EP disclosed
EP-3606913-B1 MICROBIOCIDAL OXADIAZOLE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2022-04-27 EP disclosed
EP-3606913-B1 MICROBIOCIDAL OXADIAZOLE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2022-04-27 EP disclosed
CN-109071522-B Microbicidal oxadiazole derivatives 先正达参股股份有限公司 2022-04-12 CN disclosed
CN-110461159-B Fungicidal compositions 先正达参股股份有限公司 2022-03-11 CN disclosed
CN-113979962-A Fungicidal compositions 先正达参股股份有限公司 2022-01-28 CN disclosed
CN-108137570-B Microbicidal oxadiazole derivatives 先正达参股股份有限公司 2022-01-28 CN disclosed
EP-3356358-B1 MICROBIOCIDAL OXADIAZOLE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2020-05-06 EP disclosed
CN-110799035-A Fungicidal compositions 先正达参股股份有限公司 2020-02-14 CN disclosed
EP-3606913-A1 MICROBIOCIDAL OXADIAZOLE DERIVATIVES Syngenta Participations AG (CH) 2020-02-12 EP disclosed
US-20190345150-A1 MICROBIOCIDAL OXADIAZOLE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2019-11-14 US disclosed
US-20190345150-A1 MICROBIOCIDAL OXADIAZOLE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2019-11-14 US disclosed
WO-2019011926-A1 MICROBIOCIDAL OXADIAZOLE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2019-01-17 WO disclosed
WO-2019002151-A1 FUNGICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2019-01-03 WO disclosed
WO-2018185013-A1 MICROBIOCIDAL OXADIAZOLE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2018-10-11 WO disclosed
US-20180273494-A1 MICROBIOCIDAL OXADIAZOLE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2018-09-27 US disclosed
WO-2017178549-A1 MICROBIOCIDAL OXADIAZOLE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2017-10-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240284908-A1 Fungicidal Compositions CYP51A1, CYP4X1, CYP1B1 HDAC1 404/4885HDAC6 586/4885HDAC5 716/4885
US-20250338848-A1 FUNGICIDAL COMPOSITIONS CYP3A7, DHCR7, CASP7 HDAC1 307/4885HDAC6 582/4885HDAC5 587/4885
US-20190345150-A1 MICROBIOCIDAL OXADIAZOLE DERIVATIVES PRF1, NOX1, ARG1 HDAC1 551/4885HDAC6 610/4885HDAC5 1156/4885
US-20180273494-A1 MICROBIOCIDAL OXADIAZOLE DERIVATIVES PRF1, NOX1, ARG1 HDAC1 580/4885HDAC6 592/4885HDAC5 1166/4885
US-11974572-B2 Fungicidal compositions CYP51A1, CYP4X1, CYP1B1 HDAC1 404/4885HDAC6 586/4885HDAC5 716/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.