SCHEMBL20528690

SCHEMBL20528690

Cc1cc(F)c(C(N)=NO)cc1F

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.36
LMNA P02545 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
GFER P55789 1/20 0.34
KMT2A Q03164 1/20 0.34
KDM1A O60341 3/20 0.33
GABRA1 P14867 1/20 0.31
SIGMAR1 Q99720 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20528689 1.00 GAA (0.36) GAALMNAL3MBTL1GFERKMT2A
SCHEMBL15108876 0.84
SCHEMBL17730404 0.83 GAA (0.36) GAALMNAL3MBTL1KDM1A
SCHEMBL17730402 0.83 GAA (0.36) GAALMNAL3MBTL1KDM1A
SCHEMBL12548084 0.78 KDM1A (0.33) GAALMNAL3MBTL1KDM1A
SCHEMBL18489290 0.76 GABRA1 (0.31) GABRA1SIGMAR1
SCHEMBL18489289 0.76 GABRA1 (0.31) GABRA1SIGMAR1
SCHEMBL18502978 0.76 GABRA1 (0.31) GABRA1SIGMAR1
SCHEMBL12569525 0.75 PRSS1 (0.38)
SCHEMBL13003589 0.75 DGAT1 (0.47) L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022207494-A1 3-(HETERO)ARYL-5-CHLORODIFLUOROMETHYL-1,2,4-OXADIAZOLE AS FUNGICIDE BAYER AKTIENGESELLSCHAFT (DE) 2022-10-06 WO disclosed
WO-2022207496-A1 3-(HETERO)ARYL-5-CHLORODIFLUOROMETHYL-1,2,4-OXADIAZOLE AS FUNGICIDE BAYER AKTIENGESELLSCHAFT (DE) 2022-10-06 WO disclosed
WO-2018184988-A1 MICROBIOCIDAL OXADIAZOLE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2018-10-11 WO disclosed