Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.85 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28688657 | 0.94 | TSHR (0.75) | TSHRTDP1ALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL29359563 | 0.92 | TSHR (1.00) | TSHRTDP1ALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL1101208 | 0.92 | TSHR (1.00) | TSHRTDP1ALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL146895 | 0.92 | TSHR (1.00) | TSHRTDP1ALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL31188803 | 0.90 | TSHR (0.96) | TSHRTDP1ALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL28589645 | 0.90 | TSHR (0.96) | TSHRTDP1ALDH1A1SMN1; SMN2HSD17B10 | |
| Benzene SCHEMBL28795937 | 0.90 | TSHR (0.68) | TSHRTDP1ALDH1A1SMN1; SMN2HSD17B10 | |
| Magnesium SCHEMBL11696142 | 0.90 | TSHR (0.96) | TSHRTDP1ALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL11696134 | 0.90 | TSHR (0.96) | TSHRTDP1ALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL8717819 | 0.90 | TSHR (0.96) | TSHRTDP1ALDH1A1SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3606906-B1 | HETEROGENEOUS CATALYSTS FOR THE DIRECT CARBONYLATION OF NITRO AROMATIC COMPOUNDS TO ISOCYANATES | BASF SE (DE) | 2023-12-27 | — | — | EP | disclosed |
| US-20230131205-A1 | HETEROGENEOUS CATALYSTS FOR THE DIRECT CARBONYLATION OF NITRO AROMATIC COMPOUNDS TO ISOCYANATES | BASF SE (DE) | 2023-04-27 | — | — | US | disclosed |
| US-20210002210-A1 | HETEROGENEOUS CATALYSTS FOR THE DIRECT CARBONYLATION OF NITRO AROMATIC COMPOUNDS TO ISOCYANATES | BASF SE (DE) | 2021-01-07 | — | — | US | disclosed |
| EP-3606906-A1 | HETEROGENEOUS CATALYSTS FOR THE DIRECT CARBONYLATION OF NITRO AROMATIC COMPOUNDS TO ISOCYANATES | BASF SE (DE) | 2020-02-12 | — | — | EP | disclosed |
| WO-2018185168-A1 | HETEROGENEOUS CATALYSTS FOR THE DIRECT CARBONYLATION OF NITRO AROMATIC COMPOUNDS TO ISOCYANATES | BASF SE (DE) | 2018-10-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210002210-A1 | HETEROGENEOUS CATALYSTS FOR THE DIRECT CARBONYLATION OF NITRO AROMATIC COMPOUNDS TO ISOCYANATES | IDH3B, SOD1, IDH3A | TSHR 4461/4885TDP1 3286/4885ALDH1A1 449/4885 |
| US-20230131205-A1 | HETEROGENEOUS CATALYSTS FOR THE DIRECT CARBONYLATION OF NITRO AROMATIC COMPOUNDS TO ISOCYANATES | IDH3B, SOD1, IDH3A | TSHR 4461/4885TDP1 3286/4885ALDH1A1 449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.