Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.53 |
| ▸ | MAOA | P21397 | 9/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11606889 | 0.81 | HTT (0.59) | MAOBMAOAHSD17B10MAPK1SMN1; SMN2 | |
| SCHEMBL20306594 | 0.78 | MAOB (0.44) | MAOBMAOAHSD17B10MAPK1SMN1; SMN2 | |
| SCHEMBL20529318 | 0.76 | MAOB (0.47) | MAOBMAOAHSD17B10MAPK1SMN1; SMN2 | |
| SCHEMBL3074561 | 0.74 | FFAR1 (0.60) | MAOBMAOAHSD17B10MAPK1SMN1; SMN2 | |
| SCHEMBL1018040 | 0.72 | MAOB (0.59) | MAOBMAOACA12CA2CA3 | |
| SCHEMBL941215 | 0.72 | PKM (0.47) | MAOBMAOAHSD17B10MAPK1SMN1; SMN2 | |
| SCHEMBL9696325 | 0.71 | MAOB (0.56) | MAOBMAOACA12CA2CA3 | |
| SCHEMBL28538405 | 0.71 | MAOB (0.56) | MAOBMAOACA12CA2CA3 | |
| SCHEMBL8779814 | 0.71 | MAOB (0.56) | MAOBMAOACA12CA2CA3 | |
| SCHEMBL507156 | 0.71 | MAOB (0.55) | MAOBMAOACA12CA2CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018185675-A1 | SUBSTITUTED OXOAZETIDINE ANALOGUES AS ROR GAMMA MODULATORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2018-10-11 | — | — | WO | disclosed |